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Clindamycin hydrochloride monohydrate

🥰Excellent
Catalog No. T22297Cas No. 58207-19-5
Alias Clindamycin alcoholate

Clindamycin hydrochloride monohydrate (Clindamycin alcoholate) is a protein synthesis inhibitor used orally, capable of diminishing virulence factor expression in Staphylococcus aureus at sub-minimum inhibitory concentrations (sub-MICs). It acts by suppressing Panton-Valentine leucocidin (PVL), toxic-shock-staphylococcal toxin (TSST-1), and alpha-haemolysin (Hla) production. Resistance to this compound emerges through enzymatic methylation at the antibiotic's 50S ribosomal subunit binding site (23S rRNA).

Clindamycin hydrochloride monohydrate

Clindamycin hydrochloride monohydrate

🥰Excellent
Purity: 99.59%
Catalog No. T22297Alias Clindamycin alcoholateCas No. 58207-19-5
Clindamycin hydrochloride monohydrate (Clindamycin alcoholate) is a protein synthesis inhibitor used orally, capable of diminishing virulence factor expression in Staphylococcus aureus at sub-minimum inhibitory concentrations (sub-MICs). It acts by suppressing Panton-Valentine leucocidin (PVL), toxic-shock-staphylococcal toxin (TSST-1), and alpha-haemolysin (Hla) production. Resistance to this compound emerges through enzymatic methylation at the antibiotic's 50S ribosomal subunit binding site (23S rRNA).
Pack SizePriceAvailabilityQuantity
100 mg$32In Stock
200 mg$45In Stock
500 mg$72In Stock
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Purity:99.59%
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Product Introduction

Bioactivity
Description
Clindamycin hydrochloride monohydrate (Clindamycin alcoholate) is a protein synthesis inhibitor used orally, capable of diminishing virulence factor expression in Staphylococcus aureus at sub-minimum inhibitory concentrations (sub-MICs). It acts by suppressing Panton-Valentine leucocidin (PVL), toxic-shock-staphylococcal toxin (TSST-1), and alpha-haemolysin (Hla) production. Resistance to this compound emerges through enzymatic methylation at the antibiotic's 50S ribosomal subunit binding site (23S rRNA).
AliasClindamycin alcoholate
Chemical Properties
Molecular Weight479.46
FormulaC18H36Cl2N2O6S
Cas No.58207-19-5
SmilesO.Cl.CCC[C@@H]1C[C@H](N(C)C1)C(=O)N[C@H]([C@H](C)Cl)[C@H]1O[C@H](SC)[C@H](O)[C@@H](O)[C@H]1O
Relative Density.1.31g/cm3
Storage & Solubility Information
StoragePowder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice.
Solubility Information
DMSO: 90 mg/mL (187.7 mM)
Solution Preparation Table
DMSO
1mg5mg10mg50mg
1 mM2.0857 mL10.4284 mL20.8568 mL104.2840 mL
5 mM0.4171 mL2.0857 mL4.1714 mL20.8568 mL
10 mM0.2086 mL1.0428 mL2.0857 mL10.4284 mL
20 mM0.1043 mL0.5214 mL1.0428 mL5.2142 mL
50 mM0.0417 mL0.2086 mL0.4171 mL2.0857 mL
100 mM0.0209 mL0.1043 mL0.2086 mL1.0428 mL

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Preparation method for in vivo formula: Take 50 μL DMSOTargetMol | reagent main solution, add 300 μLPEG300TargetMol | reagent mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2OTargetMol | reagent mix well and clarify
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