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L-Lactic acid

L-Lactic acid
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Purity:99.85%
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L-Lactic acid

Catalog No. T4845Cas No. 79-33-4
L-Lactic acid ((S)-2-Hydroxypropanoic acid) is a natural product produced by the anaerobic glycolysis of pyruvic acid. L-Lactic acid is a sensitive indicator of tissue hypoxia and can be used as a hemodynamic indicator in critically ill patients.
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Pack SizePriceAvailabilityQuantity
500 mg$41In Stock
1 g$48In Stock
1 mL x 10 mM (in DMSO)$45In Stock
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Product Introduction

Bioactivity
Description
L-Lactic acid ((S)-2-Hydroxypropanoic acid) is a natural product produced by the anaerobic glycolysis of pyruvic acid. L-Lactic acid is a sensitive indicator of tissue hypoxia and can be used as a hemodynamic indicator in critically ill patients.
In vitro
METHODS: Mouse CD4+CD25-T cells were treated with low-glucose medium containing L-Lactic acid (5-20 mM), and Teff proliferation was detected by Flow cytometry.
RESULTS: L-Lactic acid had a sustained inhibitory effect on T cell proliferation, and apoptosis-independent effect. [1]
METHODS: T cells were cultured in medium containing L-Lactic acid (20 mM), and ROS levels were measured using ROS and superoxide detection assay kits.
RESULTS: A significant reduction in ROS and O2- production was observed in L-Lactic acid-treated T cells. [2]
In vivo
METHODS: To study its effect on swimming endurance, L-Lactic acid (25-50 mg/kg in 0.9% NaCl) was administered intraperitoneally to ICR mice.
RESULTS: L-Lactic acid enhanced the swimming endurance of mice, and the effect was dose-dependent. [3]
METHODS: To investigate the effect on endotoxemia, L-Lactic acid (80 mg/kg) was intraperitoneally injected into mice, and 20 h later, a lethal dose of LPS (25 mg/kg) was intraperitoneally injected into mice to induce infectious shock.
RESULTS: L-Lactic acid significantly inhibited LPS-induced cytokine induction in mice following endotoxemia.L-Lactic acid treatment decreased glucose uptake and lactate output during LPS stimulation. [4]
Alias2-HYDROXYPROPIONIC ACID, L-(+)-Lactic acid, (S)-2-Hydroxypropanoic acid
Chemical Properties
Molecular Weight90.08
FormulaC3H6O3
Cas No.79-33-4
Storage & Solubility Information
Storage Powder: -20°C for 3 years | In solvent: -80°C for 1 year
Solubility Information
DMSO: 50 mg/mL (555.06 mM)
Saline: 90.08 mg/mL (555.06 mM)
Solution Preparation Table
DMSO
1mg5mg10mg50mg
1 mM11.1012 mL55.5062 mL111.0124 mL555.0622 mL
5 mM2.2202 mL11.1012 mL22.2025 mL111.0124 mL
10 mM1.1101 mL5.5506 mL11.1012 mL55.5062 mL
20 mM0.5551 mL2.7753 mL5.5506 mL27.7531 mL
50 mM0.2220 mL1.1101 mL2.2202 mL11.1012 mL
100 mM0.1110 mL0.5551 mL1.1101 mL5.5506 mL

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