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SAG 21k

🥰Excellent
Catalog No. T35559Cas No. 946002-48-8

SAG 21k is an orally bioactive and potent Hedgehog signaling activator that crosses the blood-brain barrier for the study of cartilage regeneration.

SAG 21k

SAG 21k

🥰Excellent
Purity: 99.51%
Catalog No. T35559Cas No. 946002-48-8
SAG 21k is an orally bioactive and potent Hedgehog signaling activator that crosses the blood-brain barrier for the study of cartilage regeneration.
Pack SizePriceAvailabilityQuantity
1 mg$117In Stock
5 mg$289In Stock
10 mg$433In Stock
25 mg$737In Stock
50 mg$987In Stock
100 mg$1,450In Stock
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Purity:99.51%
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Product Introduction

Bioactivity
Description
SAG 21k is an orally bioactive and potent Hedgehog signaling activator that crosses the blood-brain barrier for the study of cartilage regeneration.
Chemical Properties
Molecular Weight556.07
FormulaC29H28ClF2N3O2S
Cas No.946002-48-8
SmilesClC=1C=2C(SC1C(N(CC3=C(OC)C=CC(=C3)C=4C=CN=CC4)[C@H]5CC[C@H](NC)CC5)=O)=C(F)C=CC2F
Storage & Solubility Information
Storagestore at low temperature,keep away from direct sunlight | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice.
Solubility Information
DMSO: 12.5 mg/mL (22.48 mM)
Solution Preparation Table
DMSO
1mg5mg10mg50mg
1 mM1.7983 mL8.9917 mL17.9833 mL89.9167 mL
5 mM0.3597 mL1.7983 mL3.5967 mL17.9833 mL
10 mM0.1798 mL0.8992 mL1.7983 mL8.9917 mL
20 mM0.0899 mL0.4496 mL0.8992 mL4.4958 mL

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TargetMol | Animal experimentsFor example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent DMSO+30% PEG300+5% Tween 80+60% ddH2O. So your working solution concentration is 2 mg/mL。
Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSOTargetMol | reagent (mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.
Preparation method for in vivo formula: Take 50 μL DMSOTargetMol | reagent main solution, add 300 μLPEG300TargetMol | reagent mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2OTargetMol | reagent mix well and clarify
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