Shopping Cart
- Remove All
Your shopping cart is currently empty
Mtb ATP synthase-IN-1
🥰Excellent
Catalog No. T60877Cas No. 2642394-38-3
Mtb ATP synthase-IN-1 (compound 6ab) is a potent inhibitor of Mycobacterium tuberculosis (Mtb) ATP synthase (MIC = 0.452-0.499 μg/mL) [1] that can be used in anti-mycobacterium research, showing low cytotoxicity (Vero IC 50 > 64 μg/mL) and acceptable oral bioavailability with good metabolic stability.
Mtb ATP synthase-IN-1
🥰Excellent
Purity: 98.28%
Catalog No. T60877Cas No. 2642394-38-3
Mtb ATP synthase-IN-1 (compound 6ab) is a potent inhibitor of Mycobacterium tuberculosis (Mtb) ATP synthase (MIC = 0.452-0.499 μg/mL) [1] that can be used in anti-mycobacterium research, showing low cytotoxicity (Vero IC 50 > 64 μg/mL) and acceptable oral bioavailability with good metabolic stability.
| Pack Size | Price | Availability | Quantity |
|---|---|---|---|
| 1 mg | $38 | In Stock | |
| 5 mg | $82 | In Stock | |
| 10 mg | $118 | In Stock | |
| 25 mg | $193 | In Stock | |
| 50 mg | $286 | In Stock | |
| 100 mg | $423 | In Stock | |
| 1 mL x 10 mM (in DMSO) | $92 | In Stock |
Bulk & Custom
Add to Cart
Questions
View MoreInhibitors Related to "Mtb ATP synthase-IN-1"
Revaprazan hydrochloride
YH1885
T2405178307-42-1
Revaprazan hydrochloride (YH1885) is the hydrochloride salt form of a lipophilic, weak base with potassium-competitive acid blocking (P-CAB) activity.
- $37
Size
QTY
Sodium oleate
Sodium oleate, Oleic acid sodium salt, cis-9-Octadecenoic acid sodium salt
T36390143-19-1
Sodium oleate (cis-9-Octadecenoic acid sodium salt) (Oleic acid sodium) is an abundant monounsaturated fatty acid sodium. Sodium oleate is a Na+/K+ ATPase activator.
- $42
Size
QTY
Oleic acid
Cited
Oleate, Glycon Wo, Elaidoic acid, 9Z-Octadecenoic acid, 9-Octadecenoic Acid, 9-cis-Octadecenoic acid
T2O2668112-80-1
Oleic acid (Glycon Wo) is a natural product, a common monounsaturated fatty acid found in a variety of animal and vegetable fats and oils. Palmitic acid is a Na+/K+ ATPase activator.
- $30
Size
QTY
Citedtrans-Aconitic acid
T48614023-65-8
Trans-Aconitic acid is normally present in normal human urine, and it has been suggested that is present in larger amounts with Reye's syndrome and organic aciduria. trans-Aconitic acid is a substrate of enzyme trans-aconitate 2-methyltransferase (EC 2.1.
- $56
Size
QTY
Chlorpropamide
Diabinese
T049094-20-2
Chlorpropamide (Diabinese) is a sulfonylurea hypoglycemic agent used in the treatment of non-insulin-dependent diabetes mellitus not responding to dietary modification.
- $31
Size
QTY
Phlorizin Cited
Phloridzin, NSC 2833, Floridzin
T292260-81-1
Phlorizin (Phloridzin) is a non-selective SGLT inhibitor found in apple, for hSGLT1( Ki=300 nM) and hSGLT2( Ki=39 nM) .
- $46
Size
QTY
CitedEsomeprazole Sodium
(S)-Omeprazole sodium
T2686L161796-78-7
Esomeprazole Sodium ((S)-Omeprazole sodium) is the S-isomer of omeprazole with selective and irreversible proton pump inhibitor activity.Esomeprazole acts as an exosome inhibitor by blocking the exosome release via the inhibition of V-H+-ATPases
- $41
Size
QTY
Tirofiban hydrochloride monohydrate
Tirofiban Hydrochloride monohydrate, MK-383 Hydrochloride monohydrate
T2537150915-40-5
Tirofiban（MK383） hydrochloride monohydrate is a non-peptide glycoprotein IIb/IIIa antagonist.
- $40
Size
QTY
Trichlormethiazide
Trichlormetazid, Naqua, Metahydrin
T0114133-67-5
Trichlormethiazide (Naqua) is a short-acting, 3-dichloromethyl derivative of hydrochlorothiazide, belonging to the class of thiazide diuretics. Trichlormethiazide appears to block the active reabsorption of chloride and possibly sodium in the ascending loop of Henle, altering electrolyte transfer in the proximal tubule.
- $45
Size
QTY
Ciclopirox Cited
HOE296b
T148229342-05-0
Ciclopirox (HOE296b) exerts its action by binding to and chelating trivalent cations, such as Fe3+ and Al3+, thereby inhibiting the availability of essential co-factors for enzymes. Ciclopirox is a synthetic, broad-spectrum antifungal agent with additional antibacterial and anti-inflammatory activities. This may lead to a loss of activity of enzymes that are essential for cellular metabolism, the organization of cell wall structure and other crucial cell functions. In addition, ciclopirox exerts its anti-inflammatory activity by inhibiting 5-lipoxygenase and cyclooxygenase (COX).
- $30
Size
QTY
CitedChebulinic acid
TQ018418942-26-2
Chebulinic acid is a potent inhibitor of M. tuberculosis DNA gyrase. It also can inhibit SMAD-3 phosphorylation and H+ K+-ATPase activity.
- $67
Size
QTY
Select Batch
Purity:98.28%
Contact us for more batch information
All TargetMol products are for research purposes only and cannot be used for human consumption. We do not provide products or services to individuals. Please comply with the intended use and do not use TargetMol products for any other purpose.Product Introduction
Bioactivity
Chemical Properties
| Description | Mtb ATP synthase-IN-1 (compound 6ab) is a potent inhibitor of Mycobacterium tuberculosis (Mtb) ATP synthase (MIC = 0.452-0.499 μg/mL) [1] that can be used in anti-mycobacterium research, showing low cytotoxicity (Vero IC 50 > 64 μg/mL) and acceptable oral bioavailability with good metabolic stability. |
| Targets&IC50 | Mtb:0.452-0.499 μg/mL(MIC) |
| In vivo | In Male CD-1 mouse, Mtb ATP synthase-IN-1 ( 50 mg / kg for PO, 5 mg / kg for IV ; single dosage ; pharmacokinetics Analysis ) can be Exhibited good metabolic stability and acceptable oral bioavailability[1]. |
| Molecular Weight | 323.30 |
| Formula | C17H13N3O4 |
| Cas No. | 2642394-38-3 |
| Smiles | O=C1C(=O)C(NCC2=NC=CC=C2)=C1NC3=CC=C4OCOC4=C3 |
Storage & Solubility Information
| Storage | store at low temperature | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. | |||||||||||||||||||||||||||||||||||
| Solubility Information | DMSO: 100 mg/mL (309.31 mM), Sonication is recommended. | |||||||||||||||||||||||||||||||||||
Solution Preparation Table | ||||||||||||||||||||||||||||||||||||
DMSO
| ||||||||||||||||||||||||||||||||||||
Calculator
In Vivo Formulation Calculator (Clear solution)
Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:
For example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . A total of 10 animals were administered, and the formula you used is 5% 
DMSO+30% PEG300+5% Tween 80+60% ddH2O. So your working solution concentration is 2 mg/mL。Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSO (mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.
(mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.Preparation method for in vivo formula: Take 50 μL DMSO main solution, add 300 μLPEG300 mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2O mix well and clarify
main solution, add 300 μLPEG300 mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2O mix well and clarifyFor Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.
Dose Conversion
You can also refer to dose conversion for different animals. More Dose Conversion
Tech Support
Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc
Keywords
Preview
Related Tags: buy Mtb ATP synthase-IN-1 | purchase Mtb ATP synthase-IN-1 | Mtb ATP synthase-IN-1 cost | order Mtb ATP synthase-IN-1 | Mtb ATP synthase-IN-1 chemical structure | Mtb ATP synthase-IN-1 in vivo | Mtb ATP synthase-IN-1 formula | Mtb ATP synthase-IN-1 molecular weight
- TOP
Feedback
Hello! How can I help you today? 
Copyright © 2015-2024 TargetMol Chemicals Inc. All Rights Reserved.