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Icosabutate (NST-4016) is an orally active derivative of eicosapentaenoic acid that inhibits hepatic inflammation and fibrosis in NASH, improves cardiovascular risk profiles in statin-treated patients with residual hypertriglyceridemia, lowers triglycerides, and may be useful in studies of liver fibrosis and atherosclerosis.
Pack Size | Price | Availability | Quantity |
---|---|---|---|
1 mg | $89 | In Stock | |
5 mg | $197 | In Stock | |
10 mg | $297 | In Stock | |
25 mg | $619 | In Stock | |
50 mg | $993 | In Stock | |
100 mg | $1,630 | In Stock | |
200 mg | $2,190 | In Stock | |
1 mL x 10 mM (in DMSO) | $217 | In Stock |
Description | Icosabutate (NST-4016) is an orally active derivative of eicosapentaenoic acid that inhibits hepatic inflammation and fibrosis in NASH, improves cardiovascular risk profiles in statin-treated patients with residual hypertriglyceridemia, lowers triglycerides, and may be useful in studies of liver fibrosis and atherosclerosis. |
In vivo | In 6-8-week-old male ob/ob mice, Icosabutate (administered at 135 mg/kg/day through diet for 5 weeks) improved glucose metabolism and insulin resistance[1]. |
Alias | PRC-4016, NST-4016 |
Molecular Weight | 374.56 |
Formula | C24H38O3 |
Cas No. | 1253909-57-7 |
Smiles | CC\C=C/C\C=C/C\C=C/C\C=C/C\C=C/CCCCOC(CC)C(O)=O |
Relative Density. | 1.31g/cm3 |
Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. | |||||||||||||||||||||||||||||||||||
Solubility Information | DMSO: 80 mg/mL (213.58 mM), Sonication is recommended. | |||||||||||||||||||||||||||||||||||
Solution Preparation Table | ||||||||||||||||||||||||||||||||||||
DMSO
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