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CJ-13,610

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Catalog No. T27026Cas No. 179420-17-8
Alias CJ-13610, CJ 13610

CJ-13,610 is an orally active and nonredox-type inhibitor of 5-lipoxygenase (5-LOX). CJ-13,610 inhibits the biosynthesis of leukotriene B4 and regulates the expression of IL-6 mRNA in macrophages.

CJ-13,610

CJ-13,610

🥰Excellent
Purity: 99.64%
Catalog No. T27026Alias CJ-13610, CJ 13610Cas No. 179420-17-8
CJ-13,610 is an orally active and nonredox-type inhibitor of 5-lipoxygenase (5-LOX). CJ-13,610 inhibits the biosynthesis of leukotriene B4 and regulates the expression of IL-6 mRNA in macrophages.
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Purity:99.64%
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Product Introduction

Bioactivity
Description
CJ-13,610 is an orally active and nonredox-type inhibitor of 5-lipoxygenase (5-LOX). CJ-13,610 inhibits the biosynthesis of leukotriene B4 and regulates the expression of IL-6 mRNA in macrophages.
In vitro
CJ-13,610 dose-dependently suppresses 5-LOX product formation in ionophore A23187-stimulated polymorphonuclear in the absence of exogenous arachidonic acid with an IC50 of about 70 nM[1].
AliasCJ-13610, CJ 13610
Chemical Properties
Molecular Weight393.5
FormulaC22H23N3O2S
Cas No.179420-17-8
SmilesC(N)(=O)C1(CCOCC1)C2=CC(SC3=CC=C(C=C3)N4C(C)=NC=C4)=CC=C2
Relative Density.1.27 g/cm3 (Predicted)
Storage & Solubility Information
StoragePowder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice.

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