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Ceronapril

Catalog No. T25226Cas No. 111223-26-8
Alias SQ-29852, SQ29852, SQ 29852, Ceronaprilum

Ceronapril (SQ 29852) is an orally active and potent angiotensin-converting enzyme (ACE) inhibitor (IC50 : 36 nM) for the study of dementia and hypertension.

Ceronapril

Ceronapril

Purity: 97.94%
Catalog No. T25226Alias SQ-29852, SQ29852, SQ 29852, CeronaprilumCas No. 111223-26-8
Ceronapril (SQ 29852) is an orally active and potent angiotensin-converting enzyme (ACE) inhibitor (IC50 : 36 nM) for the study of dementia and hypertension.
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Purity:97.94%
ee:100%
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Product Introduction

Bioactivity
Description
Ceronapril (SQ 29852) is an orally active and potent angiotensin-converting enzyme (ACE) inhibitor (IC50 : 36 nM) for the study of dementia and hypertension.
In vivo
In male SD rats, Ceronapril (SQ 29852) inhibits ACE, with ED50 values of 0.063 μM/kg and 0.53 μM/kg for intravenous injection and oral administration, respectively [1]. Ceronapril (100 mg/kg; p.o.; single dose or twice daily for 3 days) blocks ACE in peripheral sites of rats [2].[1].
AliasSQ-29852, SQ29852, SQ 29852, Ceronaprilum
Chemical Properties
Molecular Weight440.47
FormulaC21H33N2O6P
Cas No.111223-26-8
Storage & Solubility Information
StoragePowder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice.

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Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSOTargetMol | reagent (mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.
Preparation method for in vivo formula: Take 50 μL DMSOTargetMol | reagent main solution, add 300 μLPEG300TargetMol | reagent mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2OTargetMol | reagent mix well and clarify
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