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Ceronapril (SQ 29852) is an orally active and potent angiotensin-converting enzyme (ACE) inhibitor (IC50 : 36 nM) for the study of dementia and hypertension.
Description | Ceronapril (SQ 29852) is an orally active and potent angiotensin-converting enzyme (ACE) inhibitor (IC50 : 36 nM) for the study of dementia and hypertension. |
In vivo | In male SD rats, Ceronapril (SQ 29852) inhibits ACE, with ED50 values of 0.063 μM/kg and 0.53 μM/kg for intravenous injection and oral administration, respectively [1]. Ceronapril (100 mg/kg; p.o.; single dose or twice daily for 3 days) blocks ACE in peripheral sites of rats [2].[1]. |
Alias | SQ-29852, SQ29852, SQ 29852, Ceronaprilum |
Molecular Weight | 440.47 |
Formula | C21H33N2O6P |
Cas No. | 111223-26-8 |
Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. |
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