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Pack Size | Price | Availability | Quantity |
---|---|---|---|
1 mg | $478 | In Stock | |
5 mg | $1,180 | In Stock | |
10 mg | $1,580 | In Stock | |
25 mg | $2,350 | In Stock | |
50 mg | $3,180 | In Stock |
Description | Suzetrigine(VX-548) is an orally active and specific NaV1.8 inhibitor. Suzetrigine has analgesic activity and can be used to study acute pain and neurotransmission. |
In vivo | As compared with placebo, VX-548 at the highest dose (a 100-mg oral loading dose of VX-548, followed by a 50-mg maintenance dose every 12 hours), but not at lower doses (a 20-mg loading dose, followed by a 10-mg maintenance dose every 12 hours), reduced acute pain over a period of 48 hours after abdominoplasty or bunionectomy.[1] |
Alias | VX-548 |
Molecular Weight | 473.39 |
Formula | C21H20F5N3O4 |
Cas No. | 2649467-58-1 |
Storage | store at low temperature,keep away from direct sunlight Powder: -20°C for 3 years | In solvent: -80°C for 1 year | |||||||||||||||||||||||||||||||||||
Solubility Information | DMSO: 100 mg/mL (211.24 mM) | |||||||||||||||||||||||||||||||||||
Solution Preparation Table | ||||||||||||||||||||||||||||||||||||
DMSO
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