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Sumatriptan
🥰Excellent
Catalog No. T23405Cas No. 103628-46-2
Alias GR 43175 free base
Sumatriptan (GR 43175 free base) is an orally active and potent 5-hydroxytryptamine 1 (5-HT1) receptor agonist that crosses the blood-brain barrier and has anti-inflammatory activity with high affinity for 5-HT1D, 5-HT1B, and 5-HT1F receptors for use in acute migraines and acute myocardial infarction.
Sumatriptan
🥰Excellent
Purity: 99.93%
Catalog No. T23405Alias GR 43175 free baseCas No. 103628-46-2
Sumatriptan (GR 43175 free base) is an orally active and potent 5-hydroxytryptamine 1 (5-HT1) receptor agonist that crosses the blood-brain barrier and has anti-inflammatory activity with high affinity for 5-HT1D, 5-HT1B, and 5-HT1F receptors for use in acute migraines and acute myocardial infarction.
| Pack Size | Price | Availability | Quantity |
|---|---|---|---|
| 10 mg | $30 | In Stock | |
| 25 mg | $45 | In Stock | |
| 50 mg | $62 | In Stock | |
| 100 mg | $89 | In Stock | |
| 500 mg | $213 | In Stock | |
| 1 mL x 10 mM (in DMSO) | $34 | In Stock |
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CitedSelect Batch
Purity:99.93%
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All TargetMol products are for research purposes only and cannot be used for human consumption. We do not provide products or services to individuals. Please comply with the intended use and do not use TargetMol products for any other purpose.Product Introduction
Bioactivity
Chemical Properties
| Description | Sumatriptan (GR 43175 free base) is an orally active and potent 5-hydroxytryptamine 1 (5-HT1) receptor agonist that crosses the blood-brain barrier and has anti-inflammatory activity with high affinity for 5-HT1D, 5-HT1B, and 5-HT1F receptors for use in acute migraines and acute myocardial infarction. |
| Targets&IC50 | 5-HT1A Receptor:100 nM (Ki), 5-HT1B Receptor:9.3 nM, 5-HT1B Receptor:27 nM (Ki), 5-HT1F Receptor:17.8 nM, 5-HT1D Receptor:17 nM (Ki), 5-HT1D Receptor:7.3 nM (IC50) |
| Alias | GR 43175 free base |
| Molecular Weight | 295.4 |
| Formula | C14H21N3O2S |
| Cas No. | 103628-46-2 |
| Smiles | O=S(=O)(NC)CC=1C=CC=2NC=C(C2C1)CCN(C)C |
| Relative Density. | 1.1778 g/cm3 (Estimated) |
Storage & Solubility Information
| Storage | keep away from moisture | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. | ||||||||||||||||||||||||||||||||||||||||
| Solubility Information | Ethanol: 40 mg/mL (93.80 mM) DMSO: 80 mg/mL (270.82 mM), Sonication is recommended. | ||||||||||||||||||||||||||||||||||||||||
Solution Preparation Table | |||||||||||||||||||||||||||||||||||||||||
Ethanol/DMSO
DMSO
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(mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.Preparation method for in vivo formula: Take 50 μL DMSO main solution, add 300 μLPEG300 mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2O mix well and clarify
main solution, add 300 μLPEG300 mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2O mix well and clarifyFor Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.
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