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3,4'-Dihydroxyflavone

Catalog No. T8263Cas No. 14919-49-4

3,4'-Dihydroxyflavone (3,4'-DHF) is an orally active flavonoid that exhibits antiviral activity against the Influenza A virus.

3,4'-Dihydroxyflavone

3,4'-Dihydroxyflavone

Purity: 97.52%
Catalog No. T8263Cas No. 14919-49-4
3,4'-Dihydroxyflavone (3,4'-DHF) is an orally active flavonoid that exhibits antiviral activity against the Influenza A virus.
Pack SizePriceAvailabilityQuantity
100 mg$66In Stock
1 mL x 10 mM (in DMSO)$72In Stock
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Purity:97.52%
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Product Introduction

Bioactivity
Description
3,4'-Dihydroxyflavone (3,4'-DHF) is an orally active flavonoid that exhibits antiviral activity against the Influenza A virus.
In vivo
'3,4'-Dihydroxyflavone (3,4'-DHF; PO, 1 mg/kg per 30 μL, daily for 5 days) significantly decreases lung virus titers and pathological changes, as well as reduces body weight loss and mortality[1].
Animal Research
Animal Model: 3,4'-Dihydroxyflavone (3,4'-DHF; PO,1 mg/kg per 30 μL,daily,5 days) significantly decreases virus titers and pathological changes in the lung and reduced body weight loss and death[1].Dosage: 1 mg/kg per 30 μL. Administration: Oral administration daily for 5 days.
Chemical Properties
Molecular Weight254.24
FormulaC15H10O4
Cas No.14919-49-4
Storage & Solubility Information
StoragePowder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice.
Solubility Information
DMSO: 155 mg/mL (69.66 mM)
Solution Preparation Table
DMSO
1mg5mg10mg50mg
1 mM3.9333 mL19.6665 mL39.3329 mL196.6646 mL
5 mM0.7867 mL3.9333 mL7.8666 mL39.3329 mL
10 mM0.3933 mL1.9666 mL3.9333 mL19.6665 mL
20 mM0.1967 mL0.9833 mL1.9666 mL9.8332 mL
50 mM0.0787 mL0.3933 mL0.7867 mL3.9333 mL

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Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:
TargetMol | Animal experimentsFor example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent DMSO+30% PEG300+5% Tween 80+60% ddH2O. So your working solution concentration is 2 mg/mL。
Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSOTargetMol | reagent (mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.
Preparation method for in vivo formula: Take 50 μL DMSOTargetMol | reagent main solution, add 300 μLPEG300TargetMol | reagent mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2OTargetMol | reagent mix well and clarify
For Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.
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