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AZD9567
🥰Excellent
Catalog No. T14386Cas No. 1893415-00-3
Alias Mizacorat
AZD9567 is a potent and orally active and selective non-steroidal glucocorticoid receptor modulator (SGRM) with an IC50 value of 3.8 nM.It has demonstrated excellent efficacy in the Streptococcus cell wall (SCW) reactivation model of joint inflammation.
AZD9567
🥰Excellent
Purity: 98.77%
Catalog No. T14386Alias MizacoratCas No. 1893415-00-3
AZD9567 is a potent and orally active and selective non-steroidal glucocorticoid receptor modulator (SGRM) with an IC50 value of 3.8 nM.It has demonstrated excellent efficacy in the Streptococcus cell wall (SCW) reactivation model of joint inflammation.
| Pack Size | Price | Availability | Quantity |
|---|---|---|---|
| 1 mg | $212 | In Stock | |
| 5 mg | $538 | In Stock | |
| 10 mg | $777 | In Stock | |
| 25 mg | $1,180 | In Stock | |
| 50 mg | $1,590 | In Stock | |
| 100 mg | $2,130 | In Stock | |
| 1 mL x 10 mM (in DMSO) | $593 | In Stock |
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Purity:98.77%
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All TargetMol products are for research purposes only and cannot be used for human consumption. We do not provide products or services to individuals. Please comply with the intended use and do not use TargetMol products for any other purpose.Product Introduction
Bioactivity
Chemical Properties
| Description | AZD9567 is a potent and orally active and selective non-steroidal glucocorticoid receptor modulator (SGRM) with an IC50 value of 3.8 nM.It has demonstrated excellent efficacy in the Streptococcus cell wall (SCW) reactivation model of joint inflammation. |
| Targets&IC50 | GR:3.8 nM |
| In vivo | AZD9567 (15 mg/kg/day; Oral gavage; daily for 8 days; female Lewis rats; sensitized by intra-articular injection of 5 μg of SCW) inhibited ankle swelling in the rat SCW model. The treatment shows excellent in vivo efficacy in a rat model of joint inflammation.[1] |
| Alias | Mizacorat |
| Molecular Weight | 494.53 |
| Formula | C27H28F2N4O3 |
| Cas No. | 1893415-00-3 |
| Smiles | CC(C)[C@H](NC(=O)C(C)(F)F)[C@H](Oc1ccc2n(ncc2c1)-c1ccc(=O)n(C)c1)c1ccccc1 |
| Relative Density. | 1.26 g/cm3 (Predicted) |
Storage & Solubility Information
| Storage | keep away from direct sunlight,store at low temperature | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. | |||||||||||||||||||||||||||||||||||
| Solubility Information | DMSO: 50 mg/mL (101.11 mM)  | |||||||||||||||||||||||||||||||||||
Solution Preparation Table | ||||||||||||||||||||||||||||||||||||
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Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:
For example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . A total of 10 animals were administered, and the formula you used is 5% 
DMSO+30% PEG300+5% Tween 80+60% ddH2O. So your working solution concentration is 2 mg/mL。Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSO (mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.
(mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.Preparation method for in vivo formula: Take 50 μL DMSO main solution, add 300 μLPEG300 mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2O mix well and clarify
main solution, add 300 μLPEG300 mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2O mix well and clarifyFor Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.
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