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Benazeprilat(CGS 14831) is an orally active active metabolite of Benazepril.Benazeprilat has potent antihypertensive activity and can be used in combination with other classes of compounds, including thiazide diuretics and calcium channel blockers, to reduce the incidence of diseases associated with cardiovascular risk and secondary end-organ damage.Benazeprilat may be be used to study acute left ventricular failure.
Pack Size | Price | Availability | Quantity |
---|---|---|---|
1 mg | $73 | In Stock | |
5 mg | $289 | In Stock | |
10 mg | $445 | In Stock | |
25 mg | $735 | In Stock | |
50 mg | $987 | In Stock | |
100 mg | $1,380 | In Stock | |
200 mg | $1,860 | In Stock |
Description | Benazeprilat(CGS 14831) is an orally active active metabolite of Benazepril.Benazeprilat has potent antihypertensive activity and can be used in combination with other classes of compounds, including thiazide diuretics and calcium channel blockers, to reduce the incidence of diseases associated with cardiovascular risk and secondary end-organ damage.Benazeprilat may be be used to study acute left ventricular failure. |
In vivo | Benazeprilat (10 mg/kg; intravenous injection; once a day for 2 days; Male SHR) and amlodipine (0.5 mg/kg, intravenous injection) in combination produce a great hypotensive effect.[2] Benazepril (0.7 mg/kg; oral) significantly alters the dynamics of systemic RAAS peptides, leading to a considerable reduction in AII and ALD, while concurrently elevating PRA and AI.[3] |
Alias | CGS-14831, CGS14831, CGS 14831 |
Molecular Weight | 396.44 |
Formula | C22H24N2O5 |
Cas No. | 86541-78-8 |
Smiles | C(C(O)=O)N1C=2C(CC[C@H](N[C@@H](CCC3=CC=CC=C3)C(O)=O)C1=O)=CC=CC2 |
Relative Density. | 1.34 g/cm3 |
Storage | store at low temperature | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. | ||||||||||
Solubility Information | DMSO: 1 mg/mL (2.52 mM), Sonication is recommended. | ||||||||||
Solution Preparation Table | |||||||||||
DMSO
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