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Benazeprilat

🥰Excellent
Catalog No. T19722Cas No. 86541-78-8
Alias CGS-14831, CGS14831, CGS 14831

Benazeprilat(CGS 14831) is an orally active active metabolite of Benazepril.Benazeprilat has potent antihypertensive activity and can be used in combination with other classes of compounds, including thiazide diuretics and calcium channel blockers, to reduce the incidence of diseases associated with cardiovascular risk and secondary end-organ damage.Benazeprilat may be be used to study acute left ventricular failure.

Benazeprilat

Benazeprilat

🥰Excellent
Purity: 98.35%
Catalog No. T19722Alias CGS-14831, CGS14831, CGS 14831Cas No. 86541-78-8
Benazeprilat(CGS 14831) is an orally active active metabolite of Benazepril.Benazeprilat has potent antihypertensive activity and can be used in combination with other classes of compounds, including thiazide diuretics and calcium channel blockers, to reduce the incidence of diseases associated with cardiovascular risk and secondary end-organ damage.Benazeprilat may be be used to study acute left ventricular failure.
Pack SizePriceAvailabilityQuantity
1 mg$73In Stock
5 mg$289In Stock
10 mg$445In Stock
25 mg$735In Stock
50 mg$987In Stock
100 mg$1,380In Stock
200 mg$1,860In Stock
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Purity:98.35%
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Product Introduction

Bioactivity
Description
Benazeprilat(CGS 14831) is an orally active active metabolite of Benazepril.Benazeprilat has potent antihypertensive activity and can be used in combination with other classes of compounds, including thiazide diuretics and calcium channel blockers, to reduce the incidence of diseases associated with cardiovascular risk and secondary end-organ damage.Benazeprilat may be be used to study acute left ventricular failure.
In vivo
Benazeprilat (10 mg/kg; intravenous injection; once a day for 2 days; Male SHR) and amlodipine (0.5 mg/kg, intravenous injection) in combination produce a great hypotensive effect.[2]
Benazepril (0.7 mg/kg; oral) significantly alters the dynamics of systemic RAAS peptides, leading to a considerable reduction in AII and ALD, while concurrently elevating PRA and AI.[3]
AliasCGS-14831, CGS14831, CGS 14831
Chemical Properties
Molecular Weight396.44
FormulaC22H24N2O5
Cas No.86541-78-8
SmilesC(C(O)=O)N1C=2C(CC[C@H](N[C@@H](CCC3=CC=CC=C3)C(O)=O)C1=O)=CC=CC2
Relative Density.1.34 g/cm3
Storage & Solubility Information
Storagestore at low temperature | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice.
Solubility Information
DMSO: 1 mg/mL (2.52 mM), Sonication is recommended.
Solution Preparation Table
DMSO
1mg5mg10mg50mg
1 mM2.5224 mL12.6122 mL25.2245 mL126.1225 mL

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