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Pack Size | Price | Availability | Quantity |
---|---|---|---|
1 mg | $75 | In Stock | |
5 mg | $315 | In Stock | |
10 mg | $593 | In Stock | |
25 mg | $1,200 | In Stock |
Description | Prinomastat (AG3340) is an orally active and selective inhibitor of metalloproteinases (MMPs) that crosses the blood-brain barrier. |
In vitro | In C57MG/Wnt1 cells, Prinomastat (0.1 µg/mL, 1 µg/mL; 4 days) significantly decreases MMP-3 promoter activity[1]. |
In vivo | In a human fibrosarcoma mouse model (HT1080), Prinomastat (50 mg/kg; intraperitoneal injection) is well tolerated by the animals, and exhibits significant tumor growth inhibition. It has a short half-life of 1.6 hours. |
Alias | KB-R9896, AG3340 |
Molecular Weight | 423.51 |
Formula | C18H21N3O5S2 |
Cas No. | 192329-42-3 |
Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | ||||||||||||||||||||||||||||||
Solubility Information | DMSO: 1 mg/mL (2.36 mM) H2O: 1 mg/mL (2.36 mM) | ||||||||||||||||||||||||||||||
Solution Preparation Table | |||||||||||||||||||||||||||||||
DMSO
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