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ICI 162,846
🥰Excellent
Catalog No. T22848Cas No. 84545-30-2
Alias ICI-162846, ICI162846, ICI 162846
ICI 162,846 is an orally active and potent H2 receptor antagonist that inhibits gastric secretion and may be used in the study of duodenal ulcers.
ICI 162,846
🥰Excellent
Purity: 99.83%
Catalog No. T22848Alias ICI-162846, ICI162846, ICI 162846Cas No. 84545-30-2
ICI 162,846 is an orally active and potent H2 receptor antagonist that inhibits gastric secretion and may be used in the study of duodenal ulcers.
| Pack Size | Price | Availability | Quantity |
|---|---|---|---|
| 1 mg | $30 | In Stock | |
| 5 mg | $63 | In Stock | |
| 10 mg | $91 | In Stock | |
| 25 mg | $148 | In Stock | |
| 50 mg | $219 | In Stock |
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Purity:99.83%
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All TargetMol products are for research purposes only and cannot be used for human consumption. We do not provide products or services to individuals. Please comply with the intended use and do not use TargetMol products for any other purpose.Product Introduction
Bioactivity
Chemical Properties
| Description | ICI 162,846 is an orally active and potent H2 receptor antagonist that inhibits gastric secretion and may be used in the study of duodenal ulcers. |
| In vivo | In CFLP mice, chronic esophageal ulcer (CDU) formation was induced by irradiating the lower mediastinum. ICI 162846 (administered at a dose of 10 mg/kg, twice daily for 5 consecutive days; via oral gavage) was able to significantly reduce the incidence of CDU [2]. |
| Alias | ICI-162846, ICI162846, ICI 162846 |
| Molecular Weight | 306.29 |
| Formula | C11H17F3N6O |
| Cas No. | 84545-30-2 |
| Smiles | O=C(N)CCCCN1N=C(C=C1)NC(=N)NCC(F)(F)F |
| Relative Density. | 1.31g/cm3 |
Storage & Solubility Information
| Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. | |||||||||||||||||||||||||
| Solubility Information | Ethanol: 10 mg/mL (32.65 mM), Sonication is recommended. DMSO: 10 mg/mL (32.65 mM, Sonication is recommended. | |||||||||||||||||||||||||
Solution Preparation Table | ||||||||||||||||||||||||||
Ethanol/DMSO
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(mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.Preparation method for in vivo formula: Take 50 μL DMSO main solution, add 300 μLPEG300 mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2O mix well and clarify
main solution, add 300 μLPEG300 mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2O mix well and clarifyFor Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.
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