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Estrogen receptor modulator 1
🥰Excellent
Catalog No. T15249Cas No. 63676-22-2
Estrogen receptor modulator 1 causes regression of Tamoxifen-resistant, hormone-independent xenograft tumors. Estrogen receptor modulator 1 is an orally active and selective estrogen receptor modulator (SERM) (pIC50: 0.46).
Estrogen receptor modulator 1
🥰Excellent
Purity: 98.14%
Catalog No. T15249Cas No. 63676-22-2
Estrogen receptor modulator 1 causes regression of Tamoxifen-resistant, hormone-independent xenograft tumors. Estrogen receptor modulator 1 is an orally active and selective estrogen receptor modulator (SERM) (pIC50: 0.46).
| Pack Size | Price | Availability | Quantity |
|---|---|---|---|
| 10 mg | $40 | In Stock | |
| 25 mg | $81 | In Stock | |
| 1 mL x 10 mM (in DMSO) | $39 | In Stock |
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Purity:98.14%
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All TargetMol products are for research purposes only and cannot be used for human consumption. We do not provide products or services to individuals. Please comply with the intended use and do not use TargetMol products for any other purpose.Product Introduction
Bioactivity
Chemical Properties
| Description | Estrogen receptor modulator 1 causes regression of Tamoxifen-resistant, hormone-independent xenograft tumors. Estrogen receptor modulator 1 is an orally active and selective estrogen receptor modulator (SERM) (pIC50: 0.46). |
| In vitro | Estrogen receptor modulator 1 (100 nM; 9 days) obviously inhibits the growth of MCF-7:5C cell. It also causes apoptosis in these cells 6 days. Estrogen receptor modulator 1 (100 nM; 10 days) inhibits T47D:A18/PKCα and T47D:A18-TAM1 colony formation [2]. |
| In vivo | Estrogen receptor modulator 1 (1.5 mg/animal; p.o.; daily for 2 weeks) induces regression of T47D:A18/PKCα tumors [2]. |
| Molecular Weight | 242.29 |
| Formula | C14H10O2S |
| Cas No. | 63676-22-2 |
| Smiles | Oc1ccc(cc1)-c1cc2ccc(O)cc2s1 |
| Relative Density. | 1.383 |
Storage & Solubility Information
| Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. | |||||||||||||||||||||||||||||||||||
| Solubility Information | DMSO: 50 mg/mL (206.36 mM)  | |||||||||||||||||||||||||||||||||||
Solution Preparation Table | ||||||||||||||||||||||||||||||||||||
DMSO
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Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:
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(mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.Preparation method for in vivo formula: Take 50 μL DMSO main solution, add 300 μLPEG300 mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2O mix well and clarify
main solution, add 300 μLPEG300 mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2O mix well and clarifyFor Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.
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