T1166 |
Ellipticine
|
Elliptisine , NSC 71795 |
Topoisomerase
|
|
Ellipticine is a potent antineoplastic agent exhibiting multiple mechanisms of action, IC50 of 0.67±0.06, 1.25±0.13, 1.2... |
T39710 |
ARV-471
|
Vepdegestrant |
Estrogen Receptor/ERR
|
|
ARV-471 is a orally active Cereblon -based estrogen receptor ( ER ) PROTAC degrader. ARV-471 is developed for the resear... |
T9912 |
Trastuzumab
|
|
EGFR
|
|
Trastuzumab is a humanized monoclonal antibody for patients with invasive breast cancers that overexpress HER2. Trastuzu... |
T41256 |
SP-96
|
|
Aurora Kinase
|
|
SP-96 is a highly effective and selective inhibitor of Aurora B with an IC50 of 0.316 nM. SP-96 shows selective growth i... |
T27093 |
CT-1
|
CT 1 |
p53
|
|
CT-1 is a DNA minor groove ligand and causes p53-dependent breast cancer cell apoptosis. |
T9720 |
T3Inh-1
|
|
Others
|
|
T3Inh-1 is an effective and selective inhibitor of ppGalNAc-T3 with an IC50 of 7 µM. T3Inh-1 prevents breast cancer cell... |
T9996 |
NCT-58
|
NCT58 |
HSP
|
|
NCT-58 is a potent C-terminal HSP90 inhibitor. NCT-58 does not induce the heat shock response (HSR). NCT-58 elicits ant... |
T3142 |
Drostanolone Propionate
|
|
Others
|
|
Dromostanolone propionate (Drostanolone propionate) is a compound has antitumor activity against breast carcinoma [1]. D... |
T3786 |
Tomatine
|
lycopersicin |
Apoptosis
,
Proteasome
|
|
An antiproliferatve agent of breast adenocarcinoma cells. |
T2503 |
PAC-1
|
Procaspase activating compound 1 |
Apoptosis
,
Caspase
,
Autophagy
|
|
PAC-1 has been used in trials studying the treatment of Lymphoma, Melanoma, Solid Tumors, Breast Cancer, and Thoracic Ca... |
T5793 |
Britannin
|
|
Apoptosis
,
Autophagy
,
AMPK
|
|
Britannin, a sesquiterpene lactone, inhibits proliferation and induces apoptosis through the mitochondrial signaling pat... |
T28543 |
RK-9123016
|
RK9123016 |
Sirtuin
|
|
RK-9123016 is a SIRT2 inhibitor. RK-9123016 increases the acetylation level of eukaryotic translation initiation factor ... |
T22094 |
JGB1741
|
ILS-JGB-1741 |
Sirtuin
|
|
JGB1741 is a potent and selective inhibitor of SIRT1 with an IC50 of 15 μM. JGB1741 modulates Bax/Bcl2 ratio, cytochrome... |
T60757 |
SB-216
|
|
|
|
SB-216 is able to be used for the research of cancer which is a potent inhibitor of tubulin polymerization. SB-216 exhi... |
T21771 |
Pyoluteorin
|
|
Antibiotic
|
|
Pyoluteorin is an antibiotic that inhibits Oomycete fungi, including the plant pathogen Pythium ultimum, and suppresses ... |
T4022 |
QS11
|
QS 11 |
GTPase
|
|
QS 11 is a GTPase activating protein of ADP-ribosylation factor 1 (ARFGAP1) inhibitor. Modulates ARF-GTP levels and syne... |
T9657 |
FiVe1
|
|
Others
|
|
FiVe1 is a vimentin binding small molecule that promotes the disintegration and phosphorylation of vimentin in the metap... |
T35528L |
TD52 dihydrochloride
|
TD52 dihydrochloride(1798328-24-1 Free base) , TD52 2HCl |
Others
|
|
TD52 dihydrochloride, an Erlotinib derivative, is an orally active, potent cancerous inhibitor of protein phosphatase 2A... |
T17258 |
WRG-28
|
|
Discoidin Domain Receptor (DDR)
|
|
WRG-28 is a potent and selective, allosteric discoidin domain receptor 2 (ddr2) inhibitor(IC50 : 230 nM) |