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Description | FMF-04-159-2 inhibits CDK14 and CDK2 with IC50s of 39.6 nM and 256 nM in NanoBRET assay, respectively. FMF-04-159-2 is a covalent CDK14 inhibitor. |
Targets&IC50 | CDK2:256 nM (in NanoBRET assay), CDK14-CyclinY:39.6 nM (in NanoBRET assay) |
In vitro | FMF-04-159-2 inhibits HCT116 cell proliferation with an IC50 of 1,144±190 nM. |
Molecular Weight | 683.01 |
Formula | C28H30Cl3N7O5S |
Cas No. | 2364489-81-4 |
Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. | |||||||||||||||||||||||||||||||||||
Solubility Information | DMSO: 250 mg/mL (366.03 mM), Sonication is recommended. | |||||||||||||||||||||||||||||||||||
Solution Preparation Table | ||||||||||||||||||||||||||||||||||||
DMSO
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