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PROTAC BRD4 Degrader-5
PROTAC BRD4 Degrader-5 is a PROTAC-based compound that efficiently degrades BRD4 in both HER2-positive and HER2-negative breast cancer cell lines[1].
Catalog No. T36242Cas No. 2409538-70-9
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PROTAC BRD4 Degrader-5
Catalog No. T36242Cas No. 2409538-70-9
PROTAC BRD4 Degrader-5 is a PROTAC-based compound that efficiently degrades BRD4 in both HER2-positive and HER2-negative breast cancer cell lines[1].
All TargetMol products are for research purposes only and cannot be used for human consumption. We do not provide products or services to individuals. Please comply with the intended use and do not use TargetMol products for any other purpose. | Pack Size | Price | Availability | Quantity |
|---|---|---|---|
| 10 mg | $996 | In Stock |
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Product Introduction
Bioactivity
Chemical Properties
| Description | PROTAC BRD4 Degrader-5 is a PROTAC-based compound that efficiently degrades BRD4 in both HER2-positive and HER2-negative breast cancer cell lines[1]. |
| In vitro | PROTAC BRD4 Degrader-5 (Compound1; 5-100 nM; 4 hours; MCF-7, MDA-MB-231, SK-BR-3, and BT-474 cells) treatment effectively degrades BRD4 in cells, as demonstrated by Western Blot Analysis[1]. |
| Alias | PROTAC BRD4 Degrader-5 |
| Molecular Weight | 1016.67 |
| Formula | C50H62ClN9O8S2 |
| Cas No. | 2409538-70-9 |
Storage & Solubility Information
| Storage | keep away from direct sunlight | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. | |||||||||||||||||||||||||||||||||||
| Solubility Information | DMSO: 145 mg/mL (142.62 mM) H2O: < 0.1 mg/mL (insoluble) | |||||||||||||||||||||||||||||||||||
Solution Preparation Table | ||||||||||||||||||||||||||||||||||||
DMSO
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Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:
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(mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.Preparation method for in vivo formula: Take 50 μL DMSO main solution, add 300 μLPEG300 mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2O mix well and clarify
main solution, add 300 μLPEG300 mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2O mix well and clarifyFor Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.
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