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Iniparib

🥰Excellent
Catalog No. T6224Cas No. 160003-66-7
Alias NSC-746045, IND-71677, BSI-201

Iniparib (BSI-201) (BSI-201) , a PARP1 inhibitor, exhibits potency in triple-negative breast Y (TNBC).

Iniparib

Iniparib

🥰Excellent
Purity: 98.28%
Catalog No. T6224Alias NSC-746045, IND-71677, BSI-201Cas No. 160003-66-7
Iniparib (BSI-201) (BSI-201) , a PARP1 inhibitor, exhibits potency in triple-negative breast Y (TNBC).
Pack SizePriceAvailabilityQuantity
5 mg$46In Stock
10 mg$70In Stock
25 mg$128In Stock
50 mg$241In Stock
100 mg$378In Stock
200 mg$600In Stock
500 mg$959In Stock
1 mL x 10 mM (in DMSO)$50In Stock
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Purity:98.28%
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Product Introduction

Bioactivity
Description
Iniparib (BSI-201) (BSI-201) , a PARP1 inhibitor, exhibits potency in triple-negative breast Y (TNBC).
In vivo
In 855-2 cells, the combination of BSI-201 (120 μM) and buthionine sulfoximine induced cell death up to 95%, which was similar to the effect on other human tumor cells. In E-ras 20 cells, BSI-201 inhibited cell growth, and its effect was enhanced 20-fold when combined with buthionine sulfoximine. BSI-201 (100 μM) inhibited the repair of ionizing radiation-induced single-strand breaks (SSBs) in human lymphocyte cell lines.
Cell Research
Cells are exposed to various concentrations of BSI-201 for 5, and 9 days in the presence or absence of buthionine sulfoxamide (BSO). After treatment, cell proliferation is measured by CellTiter-Glo assay.(Only for Reference)
AliasNSC-746045, IND-71677, BSI-201
Chemical Properties
Molecular Weight292.03
FormulaC7H5IN2O3
Cas No.160003-66-7
SmilesN(=O)(=O)C1=CC(C(N)=O)=CC=C1I
Relative Density.2.055 g/cm3 (Predicted)
Storage & Solubility Information
StoragePowder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice.
Solubility Information
Ethanol: 14.6 mg/mL (50 mM)
DMSO: 85 mg/mL (291.07 mM), Sonication is recommended.
Solution Preparation Table
Ethanol/DMSO
1mg5mg10mg50mg
1 mM3.4243 mL17.1215 mL34.2431 mL171.2153 mL
5 mM0.6849 mL3.4243 mL6.8486 mL34.2431 mL
10 mM0.3424 mL1.7122 mL3.4243 mL17.1215 mL
20 mM0.1712 mL0.8561 mL1.7122 mL8.5608 mL
50 mM0.0685 mL0.3424 mL0.6849 mL3.4243 mL
DMSO
1mg5mg10mg50mg
100 mM0.0342 mL0.1712 mL0.3424 mL1.7122 mL

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Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:
TargetMol | Animal experimentsFor example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent DMSO+30% PEG300+5% Tween 80+60% ddH2O. So your working solution concentration is 2 mg/mL。
Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSOTargetMol | reagent (mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.
Preparation method for in vivo formula: Take 50 μL DMSOTargetMol | reagent main solution, add 300 μLPEG300TargetMol | reagent mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2OTargetMol | reagent mix well and clarify
For Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.
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