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Neoprzewaquinone A
Catalog No. TN1985Cas No. 630057-39-5
Neoprzewaquinone A (NEO), an active ingredient of S. miltiorrhiza, inhibits breast cancer cell migration and promotes smooth muscle relaxation by targeting PIM1 and blocking the ROCK2/STAT3 pathway.
Neoprzewaquinone A
Catalog No. TN1985Cas No. 630057-39-5
Neoprzewaquinone A (NEO), an active ingredient of S. miltiorrhiza, inhibits breast cancer cell migration and promotes smooth muscle relaxation by targeting PIM1 and blocking the ROCK2/STAT3 pathway.
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Product Introduction
Bioactivity
Chemical Properties
| Description | Neoprzewaquinone A (NEO), an active ingredient of S. miltiorrhiza, inhibits breast cancer cell migration and promotes smooth muscle relaxation by targeting PIM1 and blocking the ROCK2/STAT3 pathway. |
| In vitro | The active ingredient Neoprzewaquinone A (NEO) in crocetin selectively inhibits PIM1,a phenomenon observed at nanomolar concentrations. NEO effectively inhibits the PIM1 kinase and significantly suppresses the growth, migration, and epithelial-mesenchymal transition (EMT) of the triple-negative breast cancer cell line MDA-MB-231 in vitro [1]. |
| Molecular Weight | 556.6 |
| Formula | C36H28O6 |
| Cas No. | 630057-39-5 |
Storage & Solubility Information
| Storage | keep away from direct sunlight,keep away from moisture | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. |
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(mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.Preparation method for in vivo formula: Take 50 μL DMSO main solution, add 300 μLPEG300 mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2O mix well and clarify
main solution, add 300 μLPEG300 mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2O mix well and clarifyFor Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.
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