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CFM 4 is a potent small molecule CARP-1/APC-2 antagonist that prevents CARP-1 from binding to APC-2, contributes to G2M cell cycle arrest, and induces apoptosis, with an IC50 in the range of 10-15 μM.CFM 4 inhibits the growth of drug-resistant human breast cancer cells.
Pack Size | Price | Availability | Quantity |
---|---|---|---|
1 mg | $36 | In Stock | |
5 mg | $80 | In Stock | |
10 mg | $128 | In Stock | |
25 mg | $263 | In Stock | |
50 mg | $393 | In Stock | |
100 mg | $576 | In Stock | |
500 mg | $1,220 | In Stock |
Description | CFM 4 is a potent small molecule CARP-1/APC-2 antagonist that prevents CARP-1 from binding to APC-2, contributes to G2M cell cycle arrest, and induces apoptosis, with an IC50 in the range of 10-15 μM.CFM 4 inhibits the growth of drug-resistant human breast cancer cells. |
Alias | CFM-4, CFM4 |
Molecular Weight | 405.9 |
Formula | C22H16ClN3OS |
Cas No. | 331458-02-7 |
Smiles | O=C1C2(C=3C(N1CC4=C(Cl)C=CC=C4)=CC=CC3)SC(=NN2)C5=CC=CC=C5 |
Relative Density. | 1.39 g/cm3 (Predicted) |
Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. | |||||||||||||||||||||||||
Solubility Information | DMSO: 20 mg/mL (49.27 mM), Sonication and heating are recommended. | |||||||||||||||||||||||||
Solution Preparation Table | ||||||||||||||||||||||||||
DMSO
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