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Demethylzeylasteral

Demethylzeylasteral
Demethylzeylasteral (T-96), isolated from Tripterygium wilfordii, has anti-inflammatory, immunosuppressive and anti-tumor activities. It inhibits the invasion of triple-negative breast cancer by blocking the TGF-β signaling pathway, and it can significantly reduce atherosclerosis.
Catalog No. T3418Cas No. 107316-88-1
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Demethylzeylasteral

Catalog No. T3418Cas No. 107316-88-1
Demethylzeylasteral (T-96), isolated from Tripterygium wilfordii, has anti-inflammatory, immunosuppressive and anti-tumor activities. It inhibits the invasion of triple-negative breast cancer by blocking the TGF-β signaling pathway, and it can significantly reduce atherosclerosis.
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Pack SizePriceAvailabilityQuantity
5 mg$45In Stock
10 mg$68In Stock
25 mg$117In Stock
50 mg$152In Stock
100 mg$197In Stock
1 mL x 10 mM (in DMSO)$50In Stock
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Product Introduction

Bioactivity
Description
Demethylzeylasteral (T-96), isolated from Tripterygium wilfordii, has anti-inflammatory, immunosuppressive and anti-tumor activities. It inhibits the invasion of triple-negative breast cancer by blocking the TGF-β signaling pathway, and it can significantly reduce atherosclerosis.
Targets&IC50
UGT1A6:0.6 μM(Ki), UGT2B7:17.3 μM(Ki)
AliasDemethylzeylasteral (T-96)
Chemical Properties
Molecular Weight480.59
FormulaC29H36O6
Cas No.107316-88-1
Storage & Solubility Information
StoragePowder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice.
Solubility Information
DMSO: 87 mg/mL (181 mM)
Solution Preparation Table
DMSO
1mg5mg10mg50mg
1 mM2.0808 mL10.4039 mL20.8078 mL104.0388 mL
5 mM0.4162 mL2.0808 mL4.1616 mL20.8078 mL
10 mM0.2081 mL1.0404 mL2.0808 mL10.4039 mL
20 mM0.1040 mL0.5202 mL1.0404 mL5.2019 mL
50 mM0.0416 mL0.2081 mL0.4162 mL2.0808 mL
100 mM0.0208 mL0.1040 mL0.2081 mL1.0404 mL

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