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Pack Size | Price | Availability | Quantity |
---|---|---|---|
5 mg | $1,920 | Backorder | |
1 mL x 10 mM (in DMSO) | $2,280 | Backorder |
Description | 5,7,3',4'-Tetrahydroxy-3-methoxy-8,5'-diprenylflavone showed strong anti-proliferation effect on ER-positive breast cancer MCF-7 cells in vitro, with an IC50 value of 4.41 uM. 5,7,3',4'-Tetrahydroxy-3-methoxy-8,5'-diprenylflavone can significantly down-regulate the expression of estrogen receptor-α (ER-α) and inhibit tumor growth in human breast cancer cell line BCAP-37 xenograft model. |
In vitro | We found that 5,7,3′,4′-tetrahydroxy-3-methoxy-8,5′-diprenylflavone showed potent anti-proliferation effects on ER-positive breast cancer MCF-7 cells in vitro (with an IC50 of 4.41 μM).[1] |
In vivo | We found that 5,7,3′,4′-tetrahydroxy-3-methoxy-8,5′-diprenylflavone strongly down-regulated expression concentrations of estrogen receptor-α (ER-α) and were able to inhibit tumor growth in a xenograft model of the human breast cancer line BCAP-37 in vivo.[1] |
Molecular Weight | 452.5 |
Formula | C26H28O7 |
Cas No. | 1353676-65-9 |
Storage | store at low temperature,keep away from direct sunlight Powder: -20°C for 3 years | In solvent: -80°C for 1 year |
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