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Ellipticine (Elliptisine) is a potent antineoplastic agent exhibiting multiple mechanisms of action, IC50 of 0.67±0.06, 1.25±0.13, 1.25±0.13, 0.67±0.06, 0.27±0.02, 0.49±0.04, 0.44±0.03, and 1.48±0.62 μM for Leukemia HL-60, Breast adenocarcinoma MCF-7, Breast adenocarcinoma MCF-7, Leukemia HL-60, Neuroblastoma IMR-32, Neuroblastoma UKF-NB-4, Neuroblastoma UKF-NB-3, and Glioblastoma U87 mg cell, respectively.
Pack Size | Price | Availability | Quantity |
---|---|---|---|
5 mg | $47 | In Stock | |
10 mg | $72 | In Stock | |
25 mg | $119 | In Stock | |
50 mg | $176 | In Stock | |
100 mg | $262 | In Stock | |
500 mg | $642 | In Stock | |
1 mL x 10 mM (in DMSO) | $50 | In Stock |
Description | Ellipticine (Elliptisine) is a potent antineoplastic agent exhibiting multiple mechanisms of action, IC50 of 0.67±0.06, 1.25±0.13, 1.25±0.13, 0.67±0.06, 0.27±0.02, 0.49±0.04, 0.44±0.03, and 1.48±0.62 μM for Leukemia HL-60, Breast adenocarcinoma MCF-7, Breast adenocarcinoma MCF-7, Leukemia HL-60, Neuroblastoma IMR-32, Neuroblastoma UKF-NB-4, Neuroblastoma UKF-NB-3, and Glioblastoma U87 mg cell, respectively. |
Targets&IC50 | MCF-7 cells:1.25±0.13μM, IMR-32 cells:0.27±0.02μM, UKF-NB-3 cells:0.44±0.03μM , U-87 MG cells (Glioblastoma):1.48±0.62 μM , UKF-NB-4 cells:0.49±0.04μM, HL-60 cells (leukemia):0.67±0.06μM |
Alias | NSC 71795, Elliptisine |
Molecular Weight | 246.31 |
Formula | C17H14N2 |
Cas No. | 519-23-3 |
Smiles | Cc1c2[nH]c3ccccc3c2c(C)c2cnccc12 |
Relative Density. | 1.257g/cm3 |
Storage | keep away from moisture | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. | |||||||||||||||||||||||||
Solubility Information | DMSO: 5 mg/mL (20.3 mM) | |||||||||||||||||||||||||
Solution Preparation Table | ||||||||||||||||||||||||||
DMSO
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