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BRD4/CK2-IN-1

Catalog No. T63991

BRD4/CK2-IN-1 is the first potent, orally active dual-target inhibitor of BRD4/CK2 (bromodomain-containing protein 4/casein kinase 2), with inhibitory concentrations (IC50) of 180 nM for BRD4 and 230 nM for CK2. In triple-negative breast cancer (TNBC), BRD4/CK2-IN-1 induces apoptosis and autophagy-related cell death.

BRD4/CK2-IN-1

BRD4/CK2-IN-1

Catalog No. T63991
BRD4/CK2-IN-1 is the first potent, orally active dual-target inhibitor of BRD4/CK2 (bromodomain-containing protein 4/casein kinase 2), with inhibitory concentrations (IC50) of 180 nM for BRD4 and 230 nM for CK2. In triple-negative breast cancer (TNBC), BRD4/CK2-IN-1 induces apoptosis and autophagy-related cell death.
Pack SizePriceAvailabilityQuantity
100 mg$1,49010-14 weeks
200 mg$2,23210-14 weeks
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Product Introduction

Bioactivity
Description
BRD4/CK2-IN-1 is the first potent, orally active dual-target inhibitor of BRD4/CK2 (bromodomain-containing protein 4/casein kinase 2), with inhibitory concentrations (IC50) of 180 nM for BRD4 and 230 nM for CK2. In triple-negative breast cancer (TNBC), BRD4/CK2-IN-1 induces apoptosis and autophagy-related cell death.
Chemical Properties
Molecular Weight564.03
FormulaC29H30ClN5O5
Storage & Solubility Information
StorageShipping with blue ice.

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