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(S)-Sunvozertinib (DZD9008) is a rationally designed selective, irreversible EGFR/HER2 inhibitor.
Pack Size | Price | Availability | Quantity |
---|---|---|---|
1 mg | $57 | In Stock | |
5 mg | $139 | In Stock | |
10 mg | $222 | In Stock | |
25 mg | $447 | In Stock | |
50 mg | $659 | In Stock | |
100 mg | $939 | In Stock | |
1 mL x 10 mM (in DMSO) | $179 | In Stock |
Description | (S)-Sunvozertinib (DZD9008) is a rationally designed selective, irreversible EGFR/HER2 inhibitor. |
Targets&IC50 | EGFR (exon 20 NPH):51.2 nM (IC50), EGFR (L858R/T790M):1 nM (IC50), EGFR (exon 20 ASV insertion):51.9 nM (IC50), HER2 exon 20 YVMA insertion:21.2 nM (IC50) |
Alias | N-[5-[[4-[5-Chloro-4-fluoro-2-(2-hydroxypropan-2-yl)anilino]pyrimidin-2-yl]amino]-2-[(3S)-3-(dimethylamino)pyrrolidin-1-yl]-4-methoxyphenyl]prop-2-enamide, DZD9008 |
Molecular Weight | 584.08 |
Formula | C29H35ClFN7O3 |
Cas No. | 2370013-49-1 |
Smiles | COc1cc(N2CC[C@@H](C2)N(C)C)c(NC(=O)C=C)cc1Nc1nccc(Nc2cc(Cl)c(F)cc2C(C)(C)O)n1 |
Relative Density. | 1.35 g/cm3 (Predicted) |
Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. | ||||||||||||||||||||||||||||||
Solubility Information | DMSO: 55 mg/ml (94.16 mM) | ||||||||||||||||||||||||||||||
Solution Preparation Table | |||||||||||||||||||||||||||||||
DMSO
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