Shopping Cart
  • Remove All
  • TargetMol
    Your shopping cart is currently empty

Lasofoxifene Tartrate

🥰Excellent
Catalog No. T7839Cas No. 190791-29-8
Alias CP-336156

Lasofoxifene Tartrate (CP-336156) is a third-generation, non-steroidal selective estrogen receptor modulator.

Lasofoxifene Tartrate

Lasofoxifene Tartrate

🥰Excellent
Purity: 98.53%
Catalog No. T7839Alias CP-336156Cas No. 190791-29-8
Lasofoxifene Tartrate (CP-336156) is a third-generation, non-steroidal selective estrogen receptor modulator.
Pack SizePriceAvailabilityQuantity
5 mg$53In Stock
10 mg$72In Stock
25 mg$142In Stock
50 mg$256In Stock
100 mg$333In Stock
1 mL x 10 mM (in DMSO)$63In Stock
Bulk & Custom
Add to Cart
Questions
View More

Related Compound Libraries of "Lasofoxifene Tartrate"

Select Batch
Purity:98.53%
Contact us for more batch information
Resource Download
All TargetMol products are for research purposes only and cannot be used for human consumption. We do not provide products or services to individuals. Please comply with the intended use and do not use TargetMol products for any other purpose.

Product Introduction

Bioactivity
Description
Lasofoxifene Tartrate (CP-336156) is a third-generation, non-steroidal selective estrogen receptor modulator.
In vivo
Lasofoxifene (LAS) and BZA reduced the clinical severity of arthritis as well as the grade of histologic synovitis and erosions on cartilage and bone.?Moreover, SERMs protected against generalised bone loss in CIA by increasing trabecular BMD.?Both SERMs decreased serum marker of cartilage destruction and LAS reduced serum IL-6 levels.?SERMs did not alter Th17 cells in lymph nodes as E2 did[1].
Animal Research
Female DBA/1 mice were ovariectomised and subjected to CIA as a model of post-menopausal RA. Mice received treatment with Lasofoxifene (LAS), BZA, 17β-estradiol (E2) as reference or vehicle. Arthritis development was assessed and BMD was determined by peripheral quantitative CT of the femurs. Serologic markers of inflammation and cartilage destruction were analysed. Immune cells in lymph nodes were studied by flow cytometry[1].
AliasCP-336156
Chemical Properties
Molecular Weight563.64
FormulaC32H37NO8
Cas No.190791-29-8
SmilesO[C@@H]([C@H](O)C(O)=O)C(O)=O.Oc1ccc2[C@H]([C@H](CCc2c1)c1ccccc1)c1ccc(OCCN2CCCC2)cc1
Relative Density.no data available
Storage & Solubility Information
StoragePowder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice.
Solubility Information
DMSO: 6 mg/mL (10.65 mM)
Solution Preparation Table
DMSO
1mg5mg10mg50mg
1 mM1.7742 mL8.8709 mL17.7418 mL88.7091 mL
5 mM0.3548 mL1.7742 mL3.5484 mL17.7418 mL
10 mM0.1774 mL0.8871 mL1.7742 mL8.8709 mL

Calculator

  • Molarity Calculator
  • Dilution Calculator
  • Reconstitution Calculator
  • Molecular Weight Calculator

In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:
TargetMol | Animal experimentsFor example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent DMSO+30% PEG300+5% Tween 80+60% ddH2O. So your working solution concentration is 2 mg/mL。
Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSOTargetMol | reagent (mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.
Preparation method for in vivo formula: Take 50 μL DMSOTargetMol | reagent main solution, add 300 μLPEG300TargetMol | reagent mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2OTargetMol | reagent mix well and clarify
For Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.
1 Enter information below:
mg/kg
g
μL
2 Enter the in vivo formulation:
% DMSO
%
%Tween 80
%ddH2O

Dose Conversion

You can also refer to dose conversion for different animals. More Dose Conversion

Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc

Keywords

Related Tags: buy Lasofoxifene Tartrate | purchase Lasofoxifene Tartrate | Lasofoxifene Tartrate cost | order Lasofoxifene Tartrate | Lasofoxifene Tartrate chemical structure | Lasofoxifene Tartrate in vivo | Lasofoxifene Tartrate formula | Lasofoxifene Tartrate molecular weight