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SB-216

🥰Excellent
Catalog No. T60757Cas No. 2756818-39-8

SB-216 is able to be used for the research of cancer which is a potent inhibitor of tubulin polymerization. SB-216 exhibits strong antiproliferative potency in a panel of human cancer cell lines, including melanoma, breast cancer, and lung cancer [1].

SB-216

SB-216

🥰Excellent
Purity: 100%
Catalog No. T60757Cas No. 2756818-39-8
SB-216 is able to be used for the research of cancer which is a potent inhibitor of tubulin polymerization. SB-216 exhibits strong antiproliferative potency in a panel of human cancer cell lines, including melanoma, breast cancer, and lung cancer [1].
Pack SizePriceAvailabilityQuantity
1 mg$49In Stock
5 mg$118In Stock
10 mg$198In Stock
25 mg$349In Stock
50 mg$499In Stock
100 mg$690In Stock
1 mL x 10 mM (in DMSO)$135In Stock
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Purity:100%
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Product Introduction

Bioactivity
Description
SB-216 is able to be used for the research of cancer which is a potent inhibitor of tubulin polymerization. SB-216 exhibits strong antiproliferative potency in a panel of human cancer cell lines, including melanoma, breast cancer, and lung cancer [1].
In vitro
SB-216 shows strong antiproliferative potency in a panel of human cancer cell lines, including melanoma, lung cancer, and breast cancer. SB-216 can be used for cancer research[1].
Chemical Properties
Molecular Weight310.35
FormulaC17H18N4O2
Cas No.2756818-39-8
SmilesCOc1ccc2N(CC(=O)Nc2c1)c1nc(C)nc2CCCc12
Storage & Solubility Information
StorageShipping with blue ice.
Solubility Information
DMSO: 58.5 mg/mL (188.5 mM), Sonication is recommended.
Solution Preparation Table
DMSO
1mg5mg10mg50mg
1 mM3.2222 mL16.1108 mL32.2217 mL161.1084 mL
5 mM0.6444 mL3.2222 mL6.4443 mL32.2217 mL
10 mM0.3222 mL1.6111 mL3.2222 mL16.1108 mL
20 mM0.1611 mL0.8055 mL1.6111 mL8.0554 mL
50 mM0.0644 mL0.3222 mL0.6444 mL3.2222 mL
100 mM0.0322 mL0.1611 mL0.3222 mL1.6111 mL

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Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:
TargetMol | Animal experimentsFor example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent DMSO+30% PEG300+5% Tween 80+60% ddH2O. So your working solution concentration is 2 mg/mL。
Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSOTargetMol | reagent (mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.
Preparation method for in vivo formula: Take 50 μL DMSOTargetMol | reagent main solution, add 300 μLPEG300TargetMol | reagent mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2OTargetMol | reagent mix well and clarify
For Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.
1 Enter information below:
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2 Enter the in vivo formulation:
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