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ON1231320

ON1231320
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Purity:98.69%
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ON1231320

Catalog No. T19664Cas No. 1312471-39-8
ON1231320 (GBO-006) is a Polo-like kinase 2 (PLK2) inhibitor.
All TargetMol products are for research purposes only and cannot be used for human consumption. We do not provide products or services to individuals. Please comply with the intended use and do not use TargetMol products for any other purpose.
Pack SizePriceAvailabilityQuantity
1 mg$40In Stock
2 mg$57In Stock
5 mg$85In Stock
10 mg$142In Stock
25 mg$288In Stock
50 mg$448In Stock
100 mg$658In Stock
1 mL x 10 mM (in DMSO)$109In Stock
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Product Introduction

Bioactivity
Description
ON1231320 (GBO-006) is a Polo-like kinase 2 (PLK2) inhibitor.
Targets&IC50
PLK3:>10 μM (IC50), PLK1:>10 μM (IC50), PLK4:>10 μM (IC50), PLK2:0.31 μM (IC50)
AliasGBO-006
Chemical Properties
Molecular Weight467.45
FormulaC22H15F2N5O3S
Cas No.1312471-39-8
Storage & Solubility Information
StoragePowder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice.
Solubility Information
DMSO: 4.67 mg/mL (10 mM)
Solution Preparation Table
DMSO
1mg5mg10mg50mg
1 mM2.1393 mL10.6963 mL21.3927 mL106.9633 mL
5 mM0.4279 mL2.1393 mL4.2785 mL21.3927 mL
10 mM0.2139 mL1.0696 mL2.1393 mL10.6963 mL

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:
TargetMol | Animal experimentsFor example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent DMSO+30% PEG300+5% Tween 80+60% ddH2O. So your working solution concentration is 2 mg/mL。
Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSOTargetMol | reagent (mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.
Preparation method for in vivo formula: Take 50 μL DMSOTargetMol | reagent main solution, add 300 μLPEG300TargetMol | reagent mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2OTargetMol | reagent mix well and clarify
1 Enter information below:
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2 Enter the in vivo formulation:
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Dose Conversion

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Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc

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