T41256 |
SP-96
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Aurora Kinase
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SP-96 is a highly effective and selective inhibitor of Aurora B with an IC50 of 0.316 nM. SP-96 shows selective growth i... |
T21771 |
Pyoluteorin
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Antibiotic
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Pyoluteorin is an antibiotic that inhibits Oomycete fungi, including the plant pathogen Pythium ultimum, and suppresses ... |
T3097 |
Mycophenolic Acid Impurity
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5,7-dihydroxy-4-methylphthalide |
Others
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Mycophenolic acid is an an immunosuppresant drug and potent anti-proliferative, and can be used in place of the older an... |
T35528L |
TD52 dihydrochloride
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TD52 dihydrochloride(1798328-24-1 Free base) , TD52 2HCl |
Others
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TD52 dihydrochloride, an Erlotinib derivative, is an orally active, potent cancerous inhibitor of protein phosphatase 2A... |
T37512 |
Cis-4-Hydroxy-L-proline
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Endogenous Metabolite
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cis-L-Hydroxyproline inhibits the synthesis and extracellular deposition of collagen. The growth inhibition of pancreati... |
T9407 |
Rasarfin
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Others
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Ras
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Rasarfin inhibits Ras and ARF6. |
T2655 |
CEP-37440
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CEP37440 |
FAK
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ALK
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CEP-37440 is an effective and specific Dual FAK/ALK inhibitor with IC50s of 120 nM(ALK cellular in 75% human plasma) and... |
T38839 |
MCX 28
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MCX 28, a triple PI3K/mTOR/PIM inhibitor, displays low nanomolar activity. |
T40182 |
Ascochlorin A
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Acremochlorin A |
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Ascochlorin A is a novel and potent hDHODH inhibitor ( K D = 3.29 μM) for treatment of triple-negative breast cancer. |
T40891 |
ADTL-SA1215
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ADTL-SA1215 is a first-in-class specific small-molecule activator of SIRT3 that modulates autophagy in triple negative b... |
T39992 |
FGFR1 inhibitor-2
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FGFR1 inhibitor-2 is a FGFR1 inhibitor ( IC 50 is 4.55 μM in MDA-MB-231 cells). FGFR1 inhibitor-2 can be used for the re... |
T25596 |
Lactiflorasyne
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Lactiflorasyne is a bioactive chemical from Artemisia lactiflora Wall that contains an ester group, a spiro system and t... |
T13889 |
SLLN-15
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Others
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SLLN-15 is an oral active, selective and potent enhancer of autophagy that activates cytostatic macroautophagy/autophagy... |
T40310 |
PARP/EZH2-IN-1
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PARP/EZH2-IN-1 is a first-in-class dual PARP ( IC 50 6.87 nM) and EZH2 ( IC 50 36.51 nM) inhibitor for triple-negative b... |
T60749 |
Autophagy-IN-2
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Autophagy-IN-2 (Compound 7h) is an inhibitor of autophagic flux which induces cancer cell apoptosis and can be used for ... |
TP2301 |
Type II collagen fragment
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Others
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Type II collagen is composed of a triple helix of three identical α chains. These molecules associate to form a fibril t... |
T39815 |
Anti-TNBC agent-1
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anti-TNBC agent-1 is a potent anti-triple-negative breast cancer (TNBC) agent. anti-TNBC agent-1 exhibits potent activit... |
T60607 |
Dasotraline
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Dasotraline is a triple reuptake inhibitor that blocks dopamine(DA), norepinephrine(NE), and serotonin [5-hydroxytryptam... |
T36868 |
4-oxo Docosahexaenoic Acid
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4-oxo Docosahexaenoic acid (4-oxo DHA) is a putative metabolite of DHA with antiproliferative and PPARγ agonist activity... |