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NCGC00378430
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Purity:99.98%
NCGC00378430
Catalog No. T9205Cas No. 920650-00-6
NCGC00378430 is a potent SIX1/EYA2 interaction inhibitor that disrupts the [SIX1/EYA2] complex, EMT, and metastasis.
All TargetMol products are for research purposes only and cannot be used for human consumption. We do not provide products or services to individuals. Please comply with the intended use and do not use TargetMol products for any other purpose. | Pack Size | Price | Availability | Quantity |
|---|---|---|---|
| 1 mg | $68 | In Stock | |
| 5 mg | $163 | In Stock | |
| 10 mg | $245 | In Stock | |
| 25 mg | $463 | In Stock | |
| 50 mg | $666 | In Stock | |
| 100 mg | $928 | In Stock | |
| 1 mL x 10 mM (in DMSO) | $179 | In Stock |
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Product Introduction
Bioactivity
Chemical Properties
Storage & Solubility Information
| Description | NCGC00378430 is a potent SIX1/EYA2 interaction inhibitor that disrupts the [SIX1/EYA2] complex, EMT, and metastasis. |
| In vitro | NCGC00378430 reduces the SIX1/EYA2 interaction.?8430 partially reversed transcriptional and metabolic profiles mediated by SIX1 overexpression and reversed SIX1-induced TGFβ signaling and EMT. |
| In vivo | NCGC00378430?was well tolerated when delivered to mice and significantly suppressed breast cancer associated metastasis in vivo without significantly altering primary tumor growth. |
| Molecular Weight | 441.5 |
| Formula | C22H23N3O5S |
| Cas No. | 920650-00-6 |
| Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. | |||||||||||||||||||||||||||||||||||
| Solubility Information | DMSO: 90 mg/mL (203.85 mM), Sonication is recommended. | |||||||||||||||||||||||||||||||||||
Solution Preparation Table | ||||||||||||||||||||||||||||||||||||
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