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Pack Size | Price | Availability | Quantity |
---|---|---|---|
1 mg | $293 | In Stock | |
5 mg | $722 | In Stock | |
10 mg | $987 | In Stock | |
25 mg | $1,520 | In Stock | |
50 mg | $1,980 | In Stock | |
100 mg | $2,500 | In Stock |
Description | VEGFR2-IN-1 is a selective and potent VEGFR2 inhibitor with antitumor activity that inhibits cell proliferation and migration and can be used in the study of breast cancer. |
In vitro | VEGFR2-IN-1 ( 0.1,1,10,100μM ; 48 h ) were effective selective inhibitors of Mcf-7, Mda-Mb-231 and Mcf-10A : MCF-7 ( IC50 = 1.18 μM ), MDA-MB-231 ( IC50 = 10.49 μM ), MCF-10A ( IC50 = 24.76 μM )[1]. |
In vivo | In Male Swiss albino mice, 21-28 g ( Xenograft model ),VEGFR2-IN-1 ( 4.2 mg/kg; i.p.; once a days ; 7 days ) Showed anticancer activity by having a tumor inhibition ratio of 54.2 % [1]. |
Molecular Weight | 398.48 |
Formula | C22H18N6S |
Cas No. | 2765224-55-1 |
Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year |
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