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Prednisolone (Hydroretrocortine) is a synthetic glucocorticoid with anti-inflammatory and immunomodulating properties.
Pack Size | Price | Availability | Quantity |
---|---|---|---|
50 mg | $29 | In Stock | |
1 mL x 10 mM (in DMSO) | $50 | In Stock |
Description | Prednisolone (Hydroretrocortine) is a synthetic glucocorticoid with anti-inflammatory and immunomodulating properties. |
In vitro | In guinea pigs, Prednisolone significantly reduces the partial pressure of oxygen in the pleural lining (PL-oxygen tension). In rats, Prednisolone (5 mg/kg) induces diaphragm contraction and histological alterations, resulting in an increased number of diaphragm bundles. |
In vivo | In quadriceps and soleus muscles, Prednisolone (0.75 mg/kg) is effective in reducing the populations of macrophages, CD4(+) T cells, CD8+ T cells, and eosinophils. At a dosage of 50 mg/kg, Prednisolone suppresses the levels of mRNA for NOS stimulated by lipopolysaccharides in neutrophils of mice. Furthermore, Prednisolone mediates its anti-inflammatory effects by decreasing the expression of cell adhesion molecules. |
Alias | Predonine, Metacortandralone, Hydroretrocortine |
Molecular Weight | 360.44 |
Formula | C21H28O5 |
Cas No. | 50-24-8 |
Smiles | CC12CC(O)C3C(CCC4=CC(=O)C=CC34C)C1CCC2(O)C(=O)CO |
Relative Density. | 1.0963 g/cm3 (Estimated) |
Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. | ||||||||||||||||||||||||||||||||||||||||
Solubility Information | Ethanol: 10 mg/mL (27.74 mM) DMSO: 45 mg/mL (124.85 mM) | ||||||||||||||||||||||||||||||||||||||||
Solution Preparation Table | |||||||||||||||||||||||||||||||||||||||||
Ethanol/DMSO
DMSO
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