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Pack Size | Price | Availability | Quantity |
---|---|---|---|
1 mg | $97 | In Stock | |
5 mg | $247 | In Stock | |
10 mg | $397 | In Stock | |
25 mg | $663 | In Stock | |
50 mg | $945 | In Stock | |
100 mg | $1,280 | In Stock | |
1 mL x 10 mM (in DMSO) | $272 | In Stock |
Description | Ropidoxuridine (IPdR) is a novel, orally available halogenated thymidine analogue that holds promise as a sensitizer for human tumors.Ropidoxuridine is an orally available and bioavailable IUdR (5-iodo-2'-deoxyuridine) prodrug. |
In vitro | Ropidoxuridine is an orally bioavailable prodrug of IUdR. Ropidoxuridine shows strong synergy effects with Alisertib at clinically relevant concentrations.[1] |
In vivo | Ropidoxuridine (750 mg/kg/day) and Alisertib (30 mg/kg/day) has strong synergy effects, in an orthotopic tumor model.[1] |
Alias | IPdR |
Molecular Weight | 338.1 |
Formula | C9H11IN2O4 |
Cas No. | 93265-81-7 |
Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | |||||||||||||||||||||||||||||||||||
Solubility Information | DMSO: 225.0 mg/mL (665.5 mM) | |||||||||||||||||||||||||||||||||||
Solution Preparation Table | ||||||||||||||||||||||||||||||||||||
DMSO
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