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Pack Size | Price | Availability | Quantity |
---|---|---|---|
2 mg | $166 | In Stock | |
25 mg | $885 | 6-8 weeks | |
50 mg | $1,150 | 6-8 weeks | |
100 mg | $1,740 | 6-8 weeks |
Description | Masoprocol (meso-Nordihydroguaiaretic acid) is a potent, orally active lipoxygenase inhibitor that exhibits antihyperglycemic activity, making it potentially valuable for type II diabetes research. In vivo, Masoprocol reduces glucose and hepatic triglyceride concentrations [1] [2] [3]. |
In vitro | Masoprocol (30 μM; 90 min) treatment of adipocytes showed elevated basal and insulin-stimulated glucose clearance in adipocytes [2]. |
In vivo | METHODS: Masoprocol (10-80 mg/kg, orally, twice daily for 4-8 days) was administered to rats fed fructose to determine whether Masoprocol could also reduce TG concentrations in rats with fructose-induced hypertriglyceridemia (HTG). RESULTS: Masoprocol administration to rats with fructose-induced HTG resulted in a decrease in serum TG levels, a decrease in hepatic TG secretion, and an increase in peripheral TG clearance. [3] |
Alias | meso-NDGA, meso-Nordihydroguaiaretic acid |
Molecular Weight | 302.37 |
Formula | C18H22O4 |
Cas No. | 27686-84-6 |
Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. | |||||||||||||||||||||||||||||||||||
Solubility Information | DMSO: 80 mg/mL (264.59 mM), Sonication is recommended. | |||||||||||||||||||||||||||||||||||
Solution Preparation Table | ||||||||||||||||||||||||||||||||||||
DMSO
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