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Masoprocol
😃Good
Catalog No. T60692Cas No. 27686-84-6
Alias meso-Nordihydroguaiaretic acid, meso-NDGA
Masoprocol (meso-Nordihydroguaiaretic acid) is a potent, orally active lipoxygenase inhibitor that exhibits antihyperglycemic activity, making it potentially valuable for type II diabetes research. In vivo, Masoprocol reduces glucose and hepatic triglyceride concentrations [1] [2] [3].
Masoprocol
😃Good
Purity: 99.76%
Catalog No. T60692Alias meso-Nordihydroguaiaretic acid, meso-NDGACas No. 27686-84-6
Masoprocol (meso-Nordihydroguaiaretic acid) is a potent, orally active lipoxygenase inhibitor that exhibits antihyperglycemic activity, making it potentially valuable for type II diabetes research. In vivo, Masoprocol reduces glucose and hepatic triglyceride concentrations [1] [2] [3].
| Pack Size | Price | Availability | Quantity |
|---|---|---|---|
| 2 mg | $166 | In Stock | |
| 25 mg | $885 | 6-8 weeks | |
| 50 mg | $1,150 | 6-8 weeks | |
| 100 mg | $1,740 | 6-8 weeks |
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CitedSelect Batch
Purity:99.76%
Contact us for more batch information
All TargetMol products are for research purposes only and cannot be used for human consumption. We do not provide products or services to individuals. Please comply with the intended use and do not use TargetMol products for any other purpose.Product Introduction
Bioactivity
Chemical Properties
| Description | Masoprocol (meso-Nordihydroguaiaretic acid) is a potent, orally active lipoxygenase inhibitor that exhibits antihyperglycemic activity, making it potentially valuable for type II diabetes research. In vivo, Masoprocol reduces glucose and hepatic triglyceride concentrations [1] [2] [3]. |
| In vitro | Masoprocol (30 μM; 90 min) treatment of adipocytes showed elevated basal and insulin-stimulated glucose clearance in adipocytes [2]. |
| In vivo | METHODS: Masoprocol (10-80 mg/kg, orally, twice daily for 4-8 days) was administered to rats fed fructose to determine whether Masoprocol could also reduce TG concentrations in rats with fructose-induced hypertriglyceridemia (HTG). RESULTS: Masoprocol administration to rats with fructose-induced HTG resulted in a decrease in serum TG levels, a decrease in hepatic TG secretion, and an increase in peripheral TG clearance. [3] |
| Alias | meso-Nordihydroguaiaretic acid, meso-NDGA |
| Molecular Weight | 302.37 |
| Formula | C18H22O4 |
| Cas No. | 27686-84-6 |
| Smiles | C([C@@H]([C@@H](CC1=CC(O)=C(O)C=C1)C)C)C2=CC(O)=C(O)C=C2 |
Storage & Solubility Information
| Storage | Shipping with blue ice. | |||||||||||||||||||||||||||||||||||
| Solubility Information | DMSO: 80 mg/mL (264.59 mM), Sonication is recommended. | |||||||||||||||||||||||||||||||||||
Solution Preparation Table | ||||||||||||||||||||||||||||||||||||
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Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:
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(mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.Preparation method for in vivo formula: Take 50 μL DMSO main solution, add 300 μLPEG300 mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2O mix well and clarify
main solution, add 300 μLPEG300 mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2O mix well and clarifyFor Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.
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