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Pack Size | Price | Availability | Quantity |
---|---|---|---|
500 mg | $39 | In Stock |
Description | Nystatin (Fungicidin) is a topical and oral antifungal agent with activity against many species of yeast and candida albicans, which is used largely to treat skin and oropharyngeal candidiasis. |
In vitro | METHODS: Hippocampal neurons were treated with Nystatin (2.5-25 µM) for 30 min and cell morphology was examined. RESULTS: Acute incubation with different concentrations of Nystatin increased the growth cone size of hippocampal neurons. [1] METHODS: CHO cells were treated with Nystatin (100-300 µmol/L) for 10-60 min, and cell viability was measured by MST-1 assay. RESULTS: Cell viability studies after Nystatin application showed significant concentration- and time-dependent effects. At Nystatin concentrations equal to 100 µmol/L, the percentage of viable cells was significantly higher compared to higher concentrations. [2] |
In vivo | Nystatin combined with endostatin selectively enhances endostatin uptake and biodistribution in tumor blood vessels and tumor tissues rather than in normal tissues of tumor-bearing mice, ultimately leading to elevated antiangiogenic and antitumor efficacies of endostatin in vivo[3]. Liposomal Nystatin, at doses as low as 2 mg/kg of body weight/day, protects neutropenic mice against Aspergillus-induced death in a statistically significant manner at the 50-day time point compared to either the no-treatment, the saline, or the empty-liposome group[4]. |
Alias | Stamycin, Fungicidin, Nystavescent |
Molecular Weight | 926.1 |
Formula | C47H75NO17 |
Cas No. | 1400-61-9 |
Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. | ||||||||||||||||||||||||||||||
Solubility Information | DMSO: 50 mg/mL (53.99 mM) ![]() | ||||||||||||||||||||||||||||||
Solution Preparation Table | |||||||||||||||||||||||||||||||
DMSO
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