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Safranal is the special volatile aroma compound of saffron.Safranal has neuroprotective and anti-inflammatory effects and has the potential for Parkinson's disease research.
Pack Size | Price | Availability | Quantity |
---|---|---|---|
500 mg | $41 | In Stock | |
1 mL x 10 mM (in DMSO) | $50 | In Stock |
Description | Safranal is the special volatile aroma compound of saffron |
In vitro | At first, the potential toxic effect of safranal on OLN-93 viability was evaluated. Also, the cells were pretreated with safranal (0.1, 1, 10, 50, 100 and 200 μM) for 2 h and then subjected to glutamic acid (16 mM) or quinolinic acid (8 mM) toxicity for 24 h, in which the same treatments were applied. Results: Safranal at concentration ranges of 1-800 μM had no toxic effect on cell viability (p>0.05). Treatment with safranal significantly increased cell viability following glutamic acid or quinolinic acid insults at concentrations higher than 1 μM (p<0.01). The cytoprotective potential of safranal was also accompanied by decreased ROS accumulation (p<0.001) and malondialdehyde level (p<0.001) following glutamic acid or quinolinic acid insults. The data suggests that safranal exhibits oligoprotection potential by means of inhibiting oxidative stress parameters. |
In vivo | Safranal (200-500 mg/kg; PO; for 7 days) slightly restores colon length and reduces weight loss percentage, significantly lowering the DAI score[2]. |
Molecular Weight | 150.22 |
Formula | C10H14O |
Cas No. | 116-26-7 |
Smiles | CC1=C(C=O)C(C)(C)CC=C1 |
Relative Density. | 0.966. Temperature:20 °C. |
Storage | store at low temperature | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. | |||||||||||||||||||||||||||||||||||
Solubility Information | DMSO: 100 mg/mL (665.69 mM), Sonication is recommended. Ethanol: 100 mg/mL (665.69 mM), Sonication is recommended. | |||||||||||||||||||||||||||||||||||
Solution Preparation Table | ||||||||||||||||||||||||||||||||||||
DMSO/Ethanol
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