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Itacitinib adipate

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Catalog No. T11687Cas No. 1334302-63-4

Itacitinib adipate is an orally bioavailable and selective JAK1 inhibitor, tested for efficacy and safety in a phase II trial in myelofibrosis.

Itacitinib adipate

Itacitinib adipate

😃Good
Catalog No. T11687Cas No. 1334302-63-4
Itacitinib adipate is an orally bioavailable and selective JAK1 inhibitor, tested for efficacy and safety in a phase II trial in myelofibrosis.
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2 mg$985 days
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Product Introduction

Bioactivity
Description
Itacitinib adipate is an orally bioavailable and selective JAK1 inhibitor, tested for efficacy and safety in a phase II trial in myelofibrosis.
Chemical Properties
Molecular Weight699.66
FormulaC32H33F4N9O5
Cas No.1334302-63-4
Relative Density.no data available
Storage & Solubility Information
StoragePowder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice.
Solubility Information
DMSO: 137.5 mg/mL (196.52 mM)
Solution Preparation Table
DMSO
1mg5mg10mg50mg
1 mM1.4293 mL7.1463 mL14.2927 mL71.4633 mL
5 mM0.2859 mL1.4293 mL2.8585 mL14.2927 mL
10 mM0.1429 mL0.7146 mL1.4293 mL7.1463 mL
20 mM0.0715 mL0.3573 mL0.7146 mL3.5732 mL
50 mM0.0286 mL0.1429 mL0.2859 mL1.4293 mL
100 mM0.0143 mL0.0715 mL0.1429 mL0.7146 mL

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Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSOTargetMol | reagent (mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.
Preparation method for in vivo formula: Take 50 μL DMSOTargetMol | reagent main solution, add 300 μLPEG300TargetMol | reagent mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2OTargetMol | reagent mix well and clarify
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