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Managlinat dialanetil

🥰Excellent
Catalog No. T16009LCas No. 280782-97-0
Alias MB06322, MB 6322, CS-917

Managlinat dialanetil (MB06322) is an orally available and potent fructose 1,6-bisphosphatase (FBPase) inhibitor with hypoglycaemic activity for the study of type 2 diabetes.

Managlinat dialanetil

Managlinat dialanetil

🥰Excellent
Purity: 98.52%
Catalog No. T16009LAlias MB06322, MB 6322, CS-917Cas No. 280782-97-0
Managlinat dialanetil (MB06322) is an orally available and potent fructose 1,6-bisphosphatase (FBPase) inhibitor with hypoglycaemic activity for the study of type 2 diabetes.
Pack SizePriceAvailabilityQuantity
1 mg$233In Stock
5 mg$578In Stock
10 mg$919In Stock
25 mg$1,380In Stock
50 mg$1,860In Stock
100 mg$2,490In Stock
500 mg$4,930In Stock
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Purity:98.52%
ee:100%
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Product Introduction

Bioactivity
Description
Managlinat dialanetil (MB06322) is an orally available and potent fructose 1,6-bisphosphatase (FBPase) inhibitor with hypoglycaemic activity for the study of type 2 diabetes.
In vivo
Dose-dependently inhibiting gluconeogenesis (GNG), managlinat dialanetil also lowers basal and postprandial blood glucose levels in Zucker diabetic fatty (ZDF) rats after oral administration[1].
AliasMB06322, MB 6322, CS-917
Chemical Properties
Molecular Weight500.55
FormulaC21H33N4O6PS
Cas No.280782-97-0
SmilesC(C(C)C)C1=C(N=C(N)S1)C=2OC(P(N[C@H](C(OCC)=O)C)(N[C@H](C(OCC)=O)C)=O)=CC2
Relative Density.1.26 g/cm3 (Predicted)
Storage & Solubility Information
StoragePowder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice.
Solubility Information
DMSO: 20 mg/mL (39.96 mM), Sonication is recommended.
Solution Preparation Table
DMSO
1mg5mg10mg50mg
1 mM1.9978 mL9.9890 mL19.9780 mL99.8901 mL
5 mM0.3996 mL1.9978 mL3.9956 mL19.9780 mL
10 mM0.1998 mL0.9989 mL1.9978 mL9.9890 mL
20 mM0.0999 mL0.4995 mL0.9989 mL4.9945 mL

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Preparation method for in vivo formula: Take 50 μL DMSOTargetMol | reagent main solution, add 300 μLPEG300TargetMol | reagent mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2OTargetMol | reagent mix well and clarify
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