Shopping Cart
- Remove All
![TargetMol](https://www.targetmol.com/storage/error/oops.webp)
Your shopping cart is currently empty
Pack Size | Price | Availability | Quantity |
---|---|---|---|
1 mg | $189 | In Stock | |
5 mg | $449 | In Stock | |
10 mg | $646 | In Stock | |
25 mg | $998 | In Stock | |
50 mg | $1,330 | In Stock | |
100 mg | $1,790 | In Stock | |
500 mg | $3,630 | In Stock | |
1 mL x 10 mM (in DMSO) | $469 | In Stock |
Description | Selurampanel (BGG492) is an orally active and selective competitive AMPA glutamate receptor antagonist, a quinazoline-dione sulfonamide. selurampanel is used in the study of epilepsy, migraine and tinnitus. |
Targets&IC50 | AMPA:190 nM |
In vivo | Selurampanel (3 mg/kg i.v.) a mouse plasma half-life of 3.3 h is determined, with a moderate volume of distribution (Vdss=1.3 L/kg) and a low clearance of 5.4 mL/min▪kg.[5] Selurampanel potently and dose-dependently antagonizes maximal electroshock seizure-induced generalized tonic-clonic seizures in mice with an ED50 value around 7 mg/kg after 1 h pre-treatment.[5] |
Alias | BGG-492, BGG 492, BGG492 |
Molecular Weight | 377.42 |
Formula | C16H19N5O4S |
Cas No. | 912574-69-7 |
Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. | ||||||||||||||||||||||||||||||
Solubility Information | DMSO: 27.5 mg/mL (72.86 mM) ![]() | ||||||||||||||||||||||||||||||
Solution Preparation Table | |||||||||||||||||||||||||||||||
DMSO
|
Copyright © 2015-2024 TargetMol Chemicals Inc. All Rights Reserved.