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L-701324

🥰Excellent
Catalog No. T1909Cas No. 142326-59-8
Alias L701324

L-701324 is an NMDA receptor with high affinity and selectivity for the glycine site, used as an orally active and long-acting anticonvulsant.

L-701324

L-701324

🥰Excellent
Purity: 100%
Catalog No. T1909Alias L701324Cas No. 142326-59-8
L-701324 is an NMDA receptor with high affinity and selectivity for the glycine site, used as an orally active and long-acting anticonvulsant.
Pack SizePriceAvailabilityQuantity
5 mg$34In Stock
10 mg$56In Stock
25 mg$98In Stock
50 mg$166In Stock
100 mg$247In Stock
200 mg$359In Stock
1 mL x 10 mM (in DMSO)$37In Stock
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Purity:100%
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Product Introduction

Bioactivity
Description
L-701324 is an NMDA receptor with high affinity and selectivity for the glycine site, used as an orally active and long-acting anticonvulsant.
Kinase Assay
Ovaries from mice at day10 of age are treated with 10 μM MHY1485 for 3h and proteins are extracted using M-PER Mammalian Protein Extraction Reagent containing a protease inhibitor cocktail. Protein concentrations in supernatants are determined by the bicinchoninic acid method. Equal amounts of protein lysates are loaded on 4-12% NuPAGE Bis-Tris gels in MOPS buffer and transferred to 0.45 μM pore nitrocellulose membranes[2].
AliasL701324
Chemical Properties
Molecular Weight363.79
FormulaC21H14ClNO3
Cas No.142326-59-8
SmilesOc1c(-c2cccc(Oc3ccccc3)c2)c(=O)[nH]c2cc(Cl)ccc12
Relative Density.1.389g/cm3
Storage & Solubility Information
StoragePowder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice.
Solubility Information
DMSO: 55 mg/mL (151.18 mM)
Solution Preparation Table
DMSO
1mg5mg10mg50mg
1 mM2.7488 mL13.7442 mL27.4884 mL137.4419 mL
5 mM0.5498 mL2.7488 mL5.4977 mL27.4884 mL
10 mM0.2749 mL1.3744 mL2.7488 mL13.7442 mL
20 mM0.1374 mL0.6872 mL1.3744 mL6.8721 mL
50 mM0.0550 mL0.2749 mL0.5498 mL2.7488 mL
100 mM0.0275 mL0.1374 mL0.2749 mL1.3744 mL

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Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:
TargetMol | Animal experimentsFor example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent DMSO+30% PEG300+5% Tween 80+60% ddH2O. So your working solution concentration is 2 mg/mL。
Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSOTargetMol | reagent (mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.
Preparation method for in vivo formula: Take 50 μL DMSOTargetMol | reagent main solution, add 300 μLPEG300TargetMol | reagent mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2OTargetMol | reagent mix well and clarify
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