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Isoproterenol

Catalog No. T21411Cas No. 7683-59-2
Alias Novodrin, Norisodrine, Medihaler-Iso, Isuprel, Isoprenaline

Isoproterenol (Norisodrine) is a non-selective and orally active β-adrenoceptor agonist.Isoproterenol is a potent peripheral vasodilator and bronchodilator.Isoproterenol can be used in the study of bradycardia and bronchial asthma for the treatment of heart block, bradycardia.

Isoproterenol

Isoproterenol

Catalog No. T21411Alias Novodrin, Norisodrine, Medihaler-Iso, Isuprel, IsoprenalineCas No. 7683-59-2
Isoproterenol (Norisodrine) is a non-selective and orally active β-adrenoceptor agonist.Isoproterenol is a potent peripheral vasodilator and bronchodilator.Isoproterenol can be used in the study of bradycardia and bronchial asthma for the treatment of heart block, bradycardia.
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1 mg$350Backorder
5 mg$828Backorder
10 mg$1,130Backorder
25 mg$1,590Backorder
50 mg$2,130Backorder
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Product Introduction

Bioactivity
Description
Isoproterenol (Norisodrine) is a non-selective and orally active β-adrenoceptor agonist.Isoproterenol is a potent peripheral vasodilator and bronchodilator.Isoproterenol can be used in the study of bradycardia and bronchial asthma for the treatment of heart block, bradycardia.
In vitro
Isoproterenol (300 nM, 3 minutes) increased the activity of low-Km cAMP Phosphodiesterase (cAMP PDE) inhibited by granule cGMP and cilotamide by about 100% in intact rat adipocytes.[1]
Isoprenaline (20 nM) increases the amplitude of total iK and causes a negative shift of approximately 10 mV in the activation curve for iK, both in the absence and in the presence of 300 nM nisoldipine to block the L-type Ca2+ current. Isoprenaline increases the spontaneous pacemaker rate of sino-atrial node pacemaker cells by 16% in rabbit-isolated pacemaker cells.[5]
In vivo
Isoproterenol (0.27-0. 64 μg/kg; oral; dog) is widely metabolized in dogs through relatively small amounts of reactions.[6]
AliasNovodrin, Norisodrine, Medihaler-Iso, Isuprel, Isoprenaline
Chemical Properties
Molecular Weight211.26
FormulaC11H17NO3
Cas No.7683-59-2
Storage & Solubility Information
StoragePowder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice.
Solubility Information
DMSO: Soluble
H2O: Insoluble

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