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Isoproterenol
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Catalog No. T21411Cas No. 7683-59-2
Alias Novodrin, Norisodrine, Medihaler-Iso, Isuprel, Isoprenaline
Isoproterenol (Norisodrine) is a non-selective and orally active β-adrenoceptor agonist.Isoproterenol is a potent peripheral vasodilator and bronchodilator.Isoproterenol can be used in the study of bradycardia and bronchial asthma for the treatment of heart block, bradycardia.
Isoproterenol
😃Good
Catalog No. T21411Alias Novodrin, Norisodrine, Medihaler-Iso, Isuprel, IsoprenalineCas No. 7683-59-2
Isoproterenol (Norisodrine) is a non-selective and orally active β-adrenoceptor agonist.Isoproterenol is a potent peripheral vasodilator and bronchodilator.Isoproterenol can be used in the study of bradycardia and bronchial asthma for the treatment of heart block, bradycardia.
| Pack Size | Price | Availability | Quantity |
|---|---|---|---|
| 1 mg | $350 | Backorder | |
| 5 mg | $828 | Backorder | |
| 10 mg | $1,130 | Backorder | |
| 25 mg | $1,590 | Backorder | |
| 50 mg | $2,130 | Backorder |
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Product Introduction
Bioactivity
Chemical Properties
| Description | Isoproterenol (Norisodrine) is a non-selective and orally active β-adrenoceptor agonist.Isoproterenol is a potent peripheral vasodilator and bronchodilator.Isoproterenol can be used in the study of bradycardia and bronchial asthma for the treatment of heart block, bradycardia. |
| In vitro | Isoproterenol (300 nM, 3 minutes) increased the activity of low-Km cAMP Phosphodiesterase (cAMP PDE) inhibited by granule cGMP and cilotamide by about 100% in intact rat adipocytes.[1] Isoprenaline (20 nM) increases the amplitude of total iK and causes a negative shift of approximately 10 mV in the activation curve for iK, both in the absence and in the presence of 300 nM nisoldipine to block the L-type Ca2+ current. Isoprenaline increases the spontaneous pacemaker rate of sino-atrial node pacemaker cells by 16% in rabbit-isolated pacemaker cells.[5] |
| In vivo | Isoproterenol (0.27-0. 64 μg/kg; oral; dog) is widely metabolized in dogs through relatively small amounts of reactions.[6] |
| Alias | Novodrin, Norisodrine, Medihaler-Iso, Isuprel, Isoprenaline |
| Molecular Weight | 211.26 |
| Formula | C11H17NO3 |
| Cas No. | 7683-59-2 |
| Relative Density. | 1.1240 g/cm3 (Estimated) |
Storage & Solubility Information
| Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. |
| Solubility Information | DMSO: Soluble H2O: Insoluble |
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(mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.Preparation method for in vivo formula: Take 50 μL DMSO main solution, add 300 μLPEG300 mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2O mix well and clarify
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