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MAO-IN-M30 dihydrochloride
🥰Excellent
Catalog No. T38034Cas No. 64821-19-8
Alias M 30 dihydrochloride
MAO-IN-M30 dihydrochloride (M 30 dihydrochloride) is a potent and brain selective monoamine oxidase (MAO) inhibitor (EC50 values are 37 and 57 nM for MAO-A and MAO-B, respectively). Also an iron chelator with antioxidant properties. Protects cells against 6-OHDA induced apoptosis. Attenuates MPTP depletion of DA and increases striatal monoamine levels in a mouse Parkinson's disease model.
MAO-IN-M30 dihydrochloride
🥰Excellent
Purity: 98.43%
Catalog No. T38034Alias M 30 dihydrochlorideCas No. 64821-19-8
MAO-IN-M30 dihydrochloride (M 30 dihydrochloride) is a potent and brain selective monoamine oxidase (MAO) inhibitor (EC50 values are 37 and 57 nM for MAO-A and MAO-B, respectively). Also an iron chelator with antioxidant properties. Protects cells against 6-OHDA induced apoptosis. Attenuates MPTP depletion of DA and increases striatal monoamine levels in a mouse Parkinson's disease model.
| Pack Size | Price | Availability | Quantity |
|---|---|---|---|
| 1 mg | $30 | In Stock | |
| 2 mg | $38 | In Stock | |
| 5 mg | $63 | In Stock | |
| 10 mg | $97 | In Stock | |
| 25 mg | $173 | In Stock | |
| 50 mg | $256 | In Stock | |
| 100 mg | $354 | In Stock | |
| 500 mg | Inquiry | In Stock |
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Purity:98.43%
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All TargetMol products are for research purposes only and cannot be used for human consumption. We do not provide products or services to individuals. Please comply with the intended use and do not use TargetMol products for any other purpose.Product Introduction
Bioactivity
Chemical Properties
| Description | MAO-IN-M30 dihydrochloride (M 30 dihydrochloride) is a potent and brain selective monoamine oxidase (MAO) inhibitor (EC50 values are 37 and 57 nM for MAO-A and MAO-B, respectively). Also an iron chelator with antioxidant properties. Protects cells against 6-OHDA induced apoptosis. Attenuates MPTP depletion of DA and increases striatal monoamine levels in a mouse Parkinson's disease model. |
| Targets&IC50 | MAO-B:57 nM (IC50), MAO-A:37 nM (IC50) |
| In vitro | MAO-IN-M30 (0.25 nM; 72 hours) significantly increased cell viability to ~90% after exposure to Dexamethasone and reduced the occurrence of fragmented DNA compared to the dexamethasone-treated group in SH-SY5Y cells[3]. Additionally, MAO-IN-M30 (0-10 μM; 24 hours) enhances PC12 cell survival[4]. |
| In vivo | MAO-IN-M30 (0.5-2.5 mg/kg; p.o.; once daily for 14 consecutive days) exhibits neuroprotective activities [6]. |
| Alias | M 30 dihydrochloride |
| Molecular Weight | 299.2 |
| Formula | C14H16Cl2N2O |
| Cas No. | 64821-19-8 |
| Smiles | Cl.Cl.CN(CC#C)Cc1ccc(O)c2ncccc12 |
| Relative Density. | no data available |
Storage & Solubility Information
| Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. | |||||||||||||||
| Solubility Information | DMSO: 1.8 mg/mL (6 mM), Sonication and heating to 60℃ are recommended. | |||||||||||||||
Solution Preparation Table | ||||||||||||||||
DMSO
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In Vivo Formulation Calculator (Clear solution)
Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:
For example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . A total of 10 animals were administered, and the formula you used is 5% 
DMSO+30% PEG300+5% Tween 80+60% ddH2O. So your working solution concentration is 2 mg/mL。Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSO (mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.
(mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.Preparation method for in vivo formula: Take 50 μL DMSO main solution, add 300 μLPEG300 mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2O mix well and clarify
main solution, add 300 μLPEG300 mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2O mix well and clarifyFor Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.
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