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MAO-IN-M30 dihydrochloride

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Purity:98.43%

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COA HNMR HPLC

MAO-IN-M30 dihydrochloride

Catalog No. T38034Cas No. 64821-19-8

MAO-IN-M30 dihydrochloride (M 30 dihydrochloride) is a potent and brain selective monoamine oxidase (MAO) inhibitor (EC50 values are 37 and 57 nM for MAO-A and MAO-B, respectively). Also an iron chelator with antioxidant properties. Protects cells against 6-OHDA induced apoptosis. Attenuates MPTP depletion of DA and increases striatal monoamine levels in a mouse Parkinson's disease model.

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Pack Size	Price	Availability
1 mg	$30	In Stock
2 mg	$38	In Stock
5 mg	$63	In Stock
10 mg	$97	In Stock
25 mg	$173	In Stock
50 mg	$256	In Stock
100 mg	$354	In Stock
500 mg	Inquiry	In Stock

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Product Introduction

Bioactivity

Description	MAO-IN-M30 dihydrochloride (M 30 dihydrochloride) is a potent and brain selective monoamine oxidase (MAO) inhibitor (EC50 values are 37 and 57 nM for MAO-A and MAO-B, respectively). Also an iron chelator with antioxidant properties. Protects cells against 6-OHDA induced apoptosis. Attenuates MPTP depletion of DA and increases striatal monoamine levels in a mouse Parkinson's disease model.
Targets&IC50	MAO-B:57 nM (IC50), MAO-A:37 nM (IC50)
In vitro	MAO-IN-M30 (0.25 nM; 72 hours) significantly increased cell viability to ~90% after exposure to Dexamethasone and reduced the occurrence of fragmented DNA compared to the dexamethasone-treated group in SH-SY5Y cells[3]. Additionally, MAO-IN-M30 (0-10 μM; 24 hours) enhances PC12 cell survival[4].
In vivo	MAO-IN-M30 (0.5-2.5 mg/kg; p.o.; once daily for 14 consecutive days) exhibits neuroprotective activities [6].
Alias	M 30 dihydrochloride

Chemical Properties

Molecular Weight	299.2
Formula	C14H16Cl2N2O
Cas No.	64821-19-8

Storage & Solubility Information

Storage

Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice.

Solubility Information

DMSO: 1.8 mg/mL (6 mM), Sonication and heating to 60℃ are recommended.

Solution Preparation Table

DMSO

	1mg	5mg	10mg	50mg
1 mM	3.3422 mL	16.7112 mL	33.4225 mL	167.1123 mL
5 mM	0.6684 mL	3.3422 mL	6.6845 mL	33.4225 mL

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:

For example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments

A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent

DMSO+30% PEG300+5% Tween 80+60% ddH2O. So your working solution concentration is 2 mg/mL。

Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSO TargetMol | reagent

(mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.

Preparation method for in vivo formula: Take 50 μL DMSO TargetMol | reagent

main solution, add 300 μLPEG300 TargetMol | reagent

mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2O TargetMol | reagent

mix well and clarify

Dose Conversion

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