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Buntanetap

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Catalog No. T17312Cas No. 116839-68-0
Alias ANVS401, ANV S401, (+)-Phenserine

Buntanetap ((+)-Phenserine) is an orally active inhibitor of polyneurotoxic proteins (TINAPs) for the study of neurological disorders, endocrine and metabolic disorders, and cardiovascular diseases.

Buntanetap

Buntanetap

🥰Excellent
Catalog No. T17312Alias ANVS401, ANV S401, (+)-PhenserineCas No. 116839-68-0
Buntanetap ((+)-Phenserine) is an orally active inhibitor of polyneurotoxic proteins (TINAPs) for the study of neurological disorders, endocrine and metabolic disorders, and cardiovascular diseases.
Pack SizePriceAvailabilityQuantity
25 mg$1,670In Stock
50 mg$2,180In Stock
100 mg$2,800In Stock
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Product Introduction

Bioactivity
Description
Buntanetap ((+)-Phenserine) is an orally active inhibitor of polyneurotoxic proteins (TINAPs) for the study of neurological disorders, endocrine and metabolic disorders, and cardiovascular diseases.
Targets&IC50
AChE:45.3 μM, AChE:(ki)48 μM
In vitro
Buntanetap (1-25 μM, 24 h) significantly decreased the expression of APP, αSYN and HTT in SH-SY5Y cells. [2]
AliasANVS401, ANV S401, (+)-Phenserine
Chemical Properties
Molecular Weight337.42
FormulaC20H23N3O2
Cas No.116839-68-0
SmilesC[C@@]12C=3C(N(C)[C@@]1(N(C)CC2)[H])=CC=C(OC(NC4=CC=CC=C4)=O)C3
Relative Density.1.228 g/cm3 (Predicted)
Storage & Solubility Information
Storagekeep away from direct sunlight | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice.
Solubility Information
DMSO: 200 mg/mL (592.73 mM), Sonication is recommended.
Solution Preparation Table
DMSO
1mg5mg10mg50mg
1 mM2.9637 mL14.8183 mL29.6367 mL148.1833 mL
5 mM0.5927 mL2.9637 mL5.9273 mL29.6367 mL
10 mM0.2964 mL1.4818 mL2.9637 mL14.8183 mL
20 mM0.1482 mL0.7409 mL1.4818 mL7.4092 mL
50 mM0.0593 mL0.2964 mL0.5927 mL2.9637 mL
100 mM0.0296 mL0.1482 mL0.2964 mL1.4818 mL

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:
TargetMol | Animal experimentsFor example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent DMSO+30% PEG300+5% Tween 80+60% ddH2O. So your working solution concentration is 2 mg/mL。
Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSOTargetMol | reagent (mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.
Preparation method for in vivo formula: Take 50 μL DMSOTargetMol | reagent main solution, add 300 μLPEG300TargetMol | reagent mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2OTargetMol | reagent mix well and clarify
For Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.
1 Enter information below:
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2 Enter the in vivo formulation:
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Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc

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