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Phenserine
Catalog No. T12446Cas No. 101246-66-6
Alias (-)-Phenserine, (-)-Eseroline phenylcarbamate
Phenserine is a derivative of Physostigmine and is annoncompetitive, long-acting and selective inhibitor of AChE.
Phenserine
Catalog No. T12446Alias (-)-Phenserine, (-)-Eseroline phenylcarbamateCas No. 101246-66-6
Phenserine is a derivative of Physostigmine and is annoncompetitive, long-acting and selective inhibitor of AChE.
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Product Introduction
Bioactivity
Chemical Properties
| Description | Phenserine is a derivative of Physostigmine and is annoncompetitive, long-acting and selective inhibitor of AChE. |
| In vitro | Phenserine treatment CHO APP751SW cell shows 18.6% reduction in cells treated with 10 μM of Phenserine, while 25 μM concentration of Phenserine reduces APP level by 51.4%[2]. |
| In vivo | cholinergic function has been impaired in a spatial memory task,Phenserine treatment improves learning [3]. |
| Alias | (-)-Phenserine, (-)-Eseroline phenylcarbamate |
| Molecular Weight | 337.42 |
| Formula | C20H23N3O2 |
| Cas No. | 101246-66-6 |
Storage & Solubility Information
| Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. |
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DMSO+30% PEG300+5% Tween 80+60% ddH2O. So your working solution concentration is 2 mg/mL。Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSO (mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.
(mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.Preparation method for in vivo formula: Take 50 μL DMSO main solution, add 300 μLPEG300 mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2O mix well and clarify
main solution, add 300 μLPEG300 mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2O mix well and clarifyFor Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.
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