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Pack Size | Price | Availability | Quantity |
---|---|---|---|
50 mg | $40 | In Stock | |
100 mg | $58 | In Stock | |
500 mg | $77 | In Stock | |
1 g | $94 | In Stock | |
1 mL x 10 mM (in DMSO) | $50 | In Stock |
Description | Ganciclovir sodium (Cytovene IV sodium) is the sodium salt of Ganciclovir with antiviral activity, especially against cytomegalovirus (CMV) and herpes simplex virus type 1 (HSV-1). |
In vitro | Ganciclovir showed activity against feline herpesvirus type-1 (FHV-1, IC50 = 5.2 microM)[1]. |
In vivo | In adult rats, the intracochlear diffusion of ganciclovir was shown to achieve the same concentration as in blood. In gestating mice, transplacental diffusion was observed, with a fetal-to-maternal blood ratio of 0.5. In newborn mice, the plasma concentration profile of ganciclovir showed a peak at 2 h followed by a gradual decrease. In adult mice, the concentration peaked at 1 h, but became undetectable by 2 h after injection. Counts of white blood cells, red blood cells and platelets decreased significantly in ganciclovir-treated newborn mice[3]. |
Alias | RS-21592 sodium, Cytovene IV sodium, 2'-Nor-2'-deoxyguanosine sodium, BW 759 sodium |
Molecular Weight | 278.22 |
Formula | C9H13N5NaO4 |
Cas No. | 107910-75-8 |
Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | ||||||||||||||||||||||||||||||||||||||||
Solubility Information | H2O: 40 mg/mL (144.29 mM) DMSO: 3.06 mg/mL (10.98 mM) ![]() | ||||||||||||||||||||||||||||||||||||||||
Solution Preparation Table | |||||||||||||||||||||||||||||||||||||||||
H2O/DMSO
H2O
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