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Chlorhexidine dihydrochloride

Catalog No. T1147Cas No. 3697-42-5
Alias NSC-185, Chlorhexidine hydrochloride, Chlorhexidine 2HCl

Chlorhexidine dihydrochloride (NSC-185) is a disinfectant and topical anti-infective agent used also as mouthwash to prevent oral plaque.

Chlorhexidine dihydrochloride

Chlorhexidine dihydrochloride

Purity: 99.39%
Catalog No. T1147Alias NSC-185, Chlorhexidine hydrochloride, Chlorhexidine 2HClCas No. 3697-42-5
Chlorhexidine dihydrochloride (NSC-185) is a disinfectant and topical anti-infective agent used also as mouthwash to prevent oral plaque.
Pack SizePriceAvailabilityQuantity
100 mg$39In Stock
500 mg$89In Stock
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Purity:99.39%
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Product Introduction

Bioactivity
Description
Chlorhexidine dihydrochloride (NSC-185) is a disinfectant and topical anti-infective agent used also as mouthwash to prevent oral plaque.
In vitro
Chlorhexidine is a chemical antiseptic.It is effective on both Gram-positive and Gram-negative bacteria, although it is less effective with some Gram-negative bacteria.It has both bactericidal and bacteriostatic mechanisms of action, the mechanism of action being membrane disruption, not ATPase inactivation as previously thought.It is also useful against fungi and enveloped viruses, though this has not been extensively investigated. Chlorhexidine is harmful in high concentrations, but is used safely in low concentrations in many products, such as mouthwash and contact lens solutions.
AliasNSC-185, Chlorhexidine hydrochloride, Chlorhexidine 2HCl
Chemical Properties
Molecular Weight578.38
FormulaC22H32Cl4N10
Cas No.3697-42-5
Storage & Solubility Information
StoragePowder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice.
Solubility Information
Ethanol: < 1 mg/mL (insoluble or slightly soluble)
DMSO: 93 mg/mL (160.8 mM)
Solution Preparation Table
DMSO
1mg5mg10mg50mg
1 mM1.7290 mL8.6448 mL17.2897 mL86.4484 mL
5 mM0.3458 mL1.7290 mL3.4579 mL17.2897 mL
10 mM0.1729 mL0.8645 mL1.7290 mL8.6448 mL
20 mM0.0864 mL0.4322 mL0.8645 mL4.3224 mL
50 mM0.0346 mL0.1729 mL0.3458 mL1.7290 mL
100 mM0.0173 mL0.0864 mL0.1729 mL0.8645 mL

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TargetMol | Animal experimentsFor example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent DMSO+30% PEG300+5% Tween 80+60% ddH2O. So your working solution concentration is 2 mg/mL。
Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSOTargetMol | reagent (mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.
Preparation method for in vivo formula: Take 50 μL DMSOTargetMol | reagent main solution, add 300 μLPEG300TargetMol | reagent mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2OTargetMol | reagent mix well and clarify
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