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Chlorhexidine digluconate
🥰Excellent
Catalog No. T14951Cas No. 18472-51-0
Chlorhexidine digluconate is a broad-spectrum antiseptic and disinfectant with broad-spectrum antimicrobial activity, inhibits both Gram-positive and Gram-negative bacteria, induces necrosis and apoptosis, and can be used in the study of bacterial infections.
Chlorhexidine digluconate
🥰Excellent
Purity: 98.53%
Catalog No. T14951Cas No. 18472-51-0
Chlorhexidine digluconate is a broad-spectrum antiseptic and disinfectant with broad-spectrum antimicrobial activity, inhibits both Gram-positive and Gram-negative bacteria, induces necrosis and apoptosis, and can be used in the study of bacterial infections.
| Pack Size | Price | Availability | Quantity |
|---|---|---|---|
| 500 mg | Inquiry | In Stock | |
| 1 g | Inquiry | In Stock | |
| 5 g | $40 | In Stock |
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Purity:98.53%
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All TargetMol products are for research purposes only and cannot be used for human consumption. We do not provide products or services to individuals. Please comply with the intended use and do not use TargetMol products for any other purpose.Product Introduction
Bioactivity
Chemical Properties
| Description | Chlorhexidine digluconate is a broad-spectrum antiseptic and disinfectant with broad-spectrum antimicrobial activity, inhibits both Gram-positive and Gram-negative bacteria, induces necrosis and apoptosis, and can be used in the study of bacterial infections. |
| In vitro | Chlorhexidine digluconate exhibits dose-dependent and time-dependent effects on Chinese hamster ovary (CHO) cells (P < 0.05). As the concentration of Chlorhexidine digluconate increases, the mode of cell death shifts from apoptosis to necrosis: Chlorhexidine digluconate (0.00005%, 0.0001%, 0.0005%; 1 hour) induces approximately 1.62%, 5.51%, and 5.47% apoptosis, while the percentages of cell necrosis are 2.38%, 8.62%, and 22.50%, respectively.[1]. |
| In vivo | Compared to mice in group D receiving only saline lavage, a single intraperitoneal injection of Chlorhexidine gluconate (0.05%, 0.025%) significantly reduces the incidence of intra-abdominal abscess formation after lavage surgery. There is no significant difference in the incidence of gross adhesions between groups of mice that have or have not undergone surgery[2]. |
| Molecular Weight | 897.76 |
| Formula | C34H54Cl2N10O14 |
| Cas No. | 18472-51-0 |
| Smiles | ClC(C=C1)=CC=C1NC(NC(NCCCCCCNC(NC(NC2=CC=C(C=C2)Cl)=N)=N)=N)=N.OC[C@@H](O)[C@@H](O)[C@H](O)[C@@H](O)C(O)=O.OC[C@@H](O)[C@@H](O)[C@H](O)[C@@H](O)C(O)=O |
| Relative Density. | 1.06g/mLat 25°C(lit.) |
Storage & Solubility Information
| Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. | |||||||||||||||||||||||||||||||||||
| Solubility Information | DMSO: 30 mg/mL (33.42 mM), Sonication is recommended. H2O: 80 mg/mL (89.11 mM), Sonication is recommended. | |||||||||||||||||||||||||||||||||||
Solution Preparation Table | ||||||||||||||||||||||||||||||||||||
DMSO/H2O
H2O
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In Vivo Formulation Calculator (Clear solution)
Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:
For example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . A total of 10 animals were administered, and the formula you used is 5% 
DMSO+30% PEG300+5% Tween 80+60% ddH2O. So your working solution concentration is 2 mg/mL。Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSO (mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.
(mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.Preparation method for in vivo formula: Take 50 μL DMSO main solution, add 300 μLPEG300 mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2O mix well and clarify
main solution, add 300 μLPEG300 mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2O mix well and clarifyFor Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.
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