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Pack Size | Price | Availability | Quantity |
---|---|---|---|
1 mg | $30 | In Stock | |
5 mg | $64 | In Stock | |
10 mg | $106 | In Stock | |
25 mg | $218 | In Stock | |
50 mg | $349 | In Stock | |
100 mg | $562 | In Stock | |
1 mL x 10 mM (in DMSO) | $71 | In Stock |
Description | DRF-1042 is an orally active camptothecin analog with antitumor activity and inhibits DNA topoisomerase I. It is used in the study of refractory tumors. |
In vitro | DRF-1042 displays excellent endostatin stability and good in vitro anticancer activity. It confronts a range of human cancer cell lines including multi-drug resistant (MDR) phenotypes [2]. |
In vivo | DRF-1042 treatment showed adverse myelosuppressive effects in clone formation assays against mouse, canine and human bone marrow cells. This supports the possibility of extending the dosing schedule in experimental and clinical studies [2]. |
Molecular Weight | 408.4 |
Formula | C22H20N2O6 |
Cas No. | 200619-13-2 |
Storage | store under nitrogen Powder: -20°C for 3 years | In solvent: -80°C for 1 year | ||||||||||||||||||||||||||||||
Solubility Information | DMSO: 30 mg/mL (73.46 mM) | ||||||||||||||||||||||||||||||
Solution Preparation Table | |||||||||||||||||||||||||||||||
DMSO
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