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5HT6-ligand-1
🥰Excellent
Catalog No. T10053Cas No. 1038988-11-2
5HT6-ligand-1 is an orally active ligand of 5-HT6 receptor (Ki = 1.43 nM).
5HT6-ligand-1
🥰Excellent
Purity: 98.95%
Catalog No. T10053Cas No. 1038988-11-2
5HT6-ligand-1 is an orally active ligand of 5-HT6 receptor (Ki = 1.43 nM).
| Pack Size | Price | Availability | Quantity |
|---|---|---|---|
| 1 mg | $118 | In Stock | |
| 5 mg | $287 | In Stock | |
| 10 mg | $392 | In Stock | |
| 25 mg | $593 | In Stock | |
| 50 mg | $798 | In Stock | |
| 100 mg | $1,050 | In Stock | |
| 200 mg | $1,390 | In Stock |
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CitedSelect Batch
Purity:98.95%
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All TargetMol products are for research purposes only and cannot be used for human consumption. We do not provide products or services to individuals. Please comply with the intended use and do not use TargetMol products for any other purpose.Product Introduction
Bioactivity
Chemical Properties
| Description | 5HT6-ligand-1 is an orally active ligand of 5-HT6 receptor (Ki = 1.43 nM). |
| Targets&IC50 | 5-HT6:ki:1.43 nM |
| In vivo | 5HT6-ligand-1(10 mg/kg) reverses the time delay-induced memory deficit and improves cognitive ability. 5HT6-ligand-1 shows an oral t1/2 of 3.17 h, a Cmax of 60 ng/mL, an exposure of 217 ng h/mL, and a bioavailability of 29%. Intravenous administration of 5HT6-ligand-1 exhibits a clearance of 220 mL/min/kg and a volume of distribution of 32.6 L/kg[1]. |
| Molecular Weight | 448.38 |
| Formula | C20H22BrN3O2S |
| Cas No. | 1038988-11-2 |
| Smiles | C(C1=C2C(N(S(=O)(=O)C3=C(Br)C=CC=C3)C=C2)=CC=C1)N4CCN(C)CC4 |
| Relative Density. | 1.47 g/cm3 (Predicted) |
Storage & Solubility Information
| Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. | |||||||||||||||||||||||||
| Solubility Information | DMSO: 10 mg/mL (22.3 mM)  | |||||||||||||||||||||||||
Solution Preparation Table | ||||||||||||||||||||||||||
DMSO
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(mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.Preparation method for in vivo formula: Take 50 μL DMSO main solution, add 300 μLPEG300 mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2O mix well and clarify
main solution, add 300 μLPEG300 mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2O mix well and clarifyFor Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.
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